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Disease
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Evidence
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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
Vitamin b1
6
Clinical Trials
2
Meta-Analyses
1
PubMed References
Top Conditions Studied with Vitamin b1
📋 Sample Trials
NCT03389555
Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
Completed · Phase 2|Phase 3
NCT03592277
Vitamin C & Thiamine to Treat Sepsis and Septic Shock
Completed · Phase 2
NCT04999137
Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa
Unknown · Phase 2
📊 Sample Meta-Analyses
CRD42021226771
The effect of vitamin C combination with vitamin B1 on patients with sepsis
Sepsis is a life-threatening organ dysfunction caused by dysregulated host respo
CRD42022330097
The efficacy of vitamin B1 (thiamine) in the treatment of septic shock: a meta-analysis of randomized controlled trials
Septic shock plays an important roles in the Intensive Care Unit. Although many
📚 Sample References
PMID 33166511
Recovery of brain cholinesterases and effect on parameters of oxidative stres and apoptosis in quails (Coturnix japonica) after chlorpyrifos and vitamin B1 administration
Chem Biol Interact · 2021
⚗️ All Ingredient data fields for Vitamin b1
⚗️ Identity
Name
Vitamin b1
Aliases / Synonyms
59-43-8; Thiamine chloride; Thiamine monochloride; Aneurine; Vitaneurin; Bethiamin; Oryzanin; Beivon; Apatate drape
🧪 Chemistry
Molecular Weight
300.8150
LogP
-2.3883
Drug-likeness
0.618
H-Bond Acceptors
5
H-Bond Donors
2
Rotatable Bonds
4
🔬 Structures
Canonical SMILES
CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.[Cl-]
Isomeric SMILES
CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.[Cl-]
InChIKey
MYVIATVLJGTBFV-UHFFFAOYSA-M
InChI
InChI=1S/C12H17N4OS.ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);1H/q+1;/p-1
🔗 External References
🔍 Raw view — every non-empty column on this row (30 fields)
name
Vitamin b1
common names
59-43-8; Thiamine chloride; Thiamine monochloride; Aneurine; Vitaneurin; Bethiamin; Oryzanin; Beivon; Apatate drape
herb ingredient id
HBIN048039
canonical smiles
CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.[Cl-]
isomeric smiles
CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO.[Cl-]
inchi
InChI=1S/C12H17N4OS.ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);1H/q+1;/p-1
inchikey
MYVIATVLJGTBFV-UHFFFAOYSA-M
mol wt
300.8150
num h acceptors
5
num h donors
2
mol logp
-2.3883
num rotatable bonds
4
drug likeness
0.618
tcmid ingredient id
22538
tcm id ingredient id
158
pubchem cid
6042
drugbank id
DB00152
npass id
NPC242203
🏥 Linked Health Topics
2 · diseases via target pathways📋 Clinical Trials
6 · subject of clinical studyNCT03389555 Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial
→ Sepsis|Septic Shock|Metabolic Disturbance
NCT03592277 Vitamin C & Thiamine to Treat Sepsis and Septic Shock
→ Sepsis|Septic Shock
NCT04999137 Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Af
→ Sepsis|Septic Shock|HIV
NCT00959075 A Trial of Thiamin Supplementation in Patients With Heart Failure
→ Heart Failure
NCT03746106 The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine
→ Vitamin B1 Deficiency|Thiamine Deficiency
NCT05840718 Supplemental Thiamine in Septic Shock: A Before-after Study
→ Septic Shock
📊 Meta-Analyses
2 · systematic reviewCRD42021226771 The effect of vitamin C combination with vitamin B1 on patients with sepsis
→ Sepsis is a life-threatening organ dysfunction cau
CRD42022330097 The efficacy of vitamin B1 (thiamine) in the treatment of septic shock: a meta-a
→ Septic shock plays an important roles in the Inten
📚 PubMed References
1 · cited researchPMID 33166511 Recovery of brain cholinesterases and effect on parameters of oxidative stres an
Chem Biol Interact
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables