Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿

Herb

→

→

→

→

🧪

Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

Quick picks: Taxol Oxytocin Morphine (?)-nicotine Testosterone Melatonin Caffeine L-ascorbic acid Progesterone Coumarins

⚗️ Ingredient

Volon

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Volon

Diabetic macular edema 3 Macular edema (ME) is secondary to many different ocular and 3 Keloid|Stem Cell 2 Hidradenitis suppurativa (HS) is a painful inflammatory diso 1 Atopic Dermatitis 1 Sudden sensorineural hearing loss (SSNHL) is a subset of Sud 1 Diabetic macular edema is the major cause of vision loss due 1 Acne Vulgaris 1 Pediatric cataract is a clouding of the lens in a child's ey 1 Osteoarthritis (OA) is the most common degenerative joint di 1 Cataracts are clouding of the naturally transparent lens of 1 Osteoarthritis (OA) is a degenerative joint disease associat 1

📋 Sample Trials

NCT06170593

Intralesional Injections of Triamcinolone for Acne Vulgaris

Completed

NCT05997238

Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA

Completed · Phase 4

NCT06079645

Lichen Sclerosus - Treatment With Triamcinolone Acetonide: Injections (Syringe and Needle) x Micro Injections (MMP Technique)

Recruiting · Phase 4

📊 Sample Meta-Analyses

CRD42018118184

Effectiveness comparison of brachytherapy and triamcinolone for keloids after surgical excision

Keloid is benign fibroproliferative disease which caused by excessive fibroblast

CRD42022346087

Triamcinolone Acetonide versus Fluticasone Propionate for rhinitis

Allergic rhinitis (AR), the most common form of rhinitis, is a global health pro

CRD42012003184

Intralesional triamcinolone acetonide injection for the treatment of hypertrophic scars and keloids: a systematic review

📚 Sample References

None linked yet.

⚗️ All Ingredient data fields for Volon

⚗️ Identity

Name

Volon

Aliases / Synonyms

triamcinolone; 124-94-7; Fluoxyprednisolone; Aristocort; Triamcinolon; Kenacort; Rodinolone; Delphicort; Ledercort; Tricortale

🧪 Chemistry

Molecular Weight

394.4390

LogP

0.6205

Drug-likeness

0.546

Oral Bioavailability

35.4230

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC43C)F)O

Isomeric SMILES

C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O

InChIKey

GFNANZIMVAIWHM-OBYCQNJPSA-N

InChI

InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1

🔗 External References

HERB DB

PubChem CID

CAS Number

DrugBank

SymMap

8404

TCMSP

MOL006859

🔍 Raw view — every non-empty column on this row (31 fields)

name

Volon

common names

triamcinolone; 124-94-7; Fluoxyprednisolone; Aristocort; Triamcinolon; Kenacort; Rodinolone; Delphicort; Ledercort; Tricortale

herb ingredient id

HBIN048161

canonical smiles

CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC43C)F)O

isomeric smiles

C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O

inchi

InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1

inchikey

GFNANZIMVAIWHM-OBYCQNJPSA-N

mol wt

394.4390

num h acceptors

num h donors

mol logp

0.6205

num rotatable bonds

drug likeness

0.546

ob score

35.4230

cas id

83474-03-7

symmap mol id

8404

tcmsp ingredient id

MOL006859

pubchem cid

31307

drugbank id

DB00620

🏥 Linked Health Topics

3 · studied for these conditions (text bridge)

📋 Clinical Trials

8 · subject of clinical study

NCT06170593 Intralesional Injections of Triamcinolone for Acne Vulgaris

→ Acne Vulgaris

NCT05997238 Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA

→ Osteoarthritis, Knee

NCT06079645 Lichen Sclerosus - Treatment With Triamcinolone Acetonide: Injections (Syringe a

→ Lichen Sclerosus of External Female Genital Organs

NCT05806021 The Efficacy of Intra-articular Triamcinolone Acetonide 5mg vs. 10 mg vs. 40 mg

→ Primary Gonarthrosis

NCT05844618 Short-Term Efficacy of Triamcinolone Acetonide (Aristocort® C) in Subjects with

→ Atopic Dermatitis

NCT05939817 The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, It

→ Keloid|Stem Cell

NCT05887804 Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilic

→ Keloid|Stem Cell

NCT06069804 Triamcinolone Acetonide as an Adjuvant to Pre-emptive Scalp Infiltration for Rel

→ Pain, Postoperative

📊 Meta-Analyses

12 · systematic review

CRD42018118184 Effectiveness comparison of brachytherapy and triamcinolone for keloids after su

→ Keloid is benign fibroproliferative disease which

CRD42022346087 Triamcinolone Acetonide versus Fluticasone Propionate for rhinitis

→ Allergic rhinitis (AR), the most common form of rh

CRD42012003184 Intralesional triamcinolone acetonide injection for the treatment of hypertrophi

CRD42019142925 Efficacy and safety of intralesional triamcinolone versus combination of triamci

→ The purpose of the study is that adds to evidence

CRD42020202254 Effect of Triamcinolone following Internal Urethrotomy to reduce recurrent ureth

→ Urethral stricture

CRD42020202976 Efficacy of Intra-articular Triamcinolone Acetonide in the Treatment of Knee Ost

→ Osteoarthritis (OA) is the most common degenerativ

CRD42022319475 The effect and safety of subconjunctival injection triamcinolone acetonide in th

→ Diabetic macular edema

CRD42022324039 The effect of posterior sub-tenon’s injection of triamcinolone acetonide combine

→ Diabetic macular edema

CRD42022328623 The effect and safety of subconjunctival injection triamcinolone acetonide in th

→ Macular edema secondary to uveitis

CRD42022356621 Comparative effcacy and safety of triamcinolone acetonide for treatment of macul

→ Macular edema (ME) is secondary to many different

CRD42022366499 Comparative effcacy of triamcinolone acetonide for treatment of macular edema by

→ Macular edema (ME) is secondary to many different

CRD42022366513 Comparative safety of triamcinolone acetonide for treatment of macular edema by

→ Macular edema (ME) is secondary to many different

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
Ingredient ↔ Target: empty — needs HERB_ingredient_target import
Target ↔ Disease: empty — needs HERB_target_disease import
Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables