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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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🌿 Herb

Silybum Marianum; Fruit of Silybum Marianum

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with Silybum Marianum; Fruit of Silybum Marianum

Metabolic Associated Fatty Liver Disease 1 Hepatitis C 1 obesity 1 Herbal medicine interventions for wound healing, investigate 1

📋 Sample Trials

NCT01292161

Effects of Silybum Marianum on Treatment of Patients With Chronic Hepatitis C

Completed · Phase 2

NCT05913986

Supplementation With Alpha-lipoic Acid and Silybum Marianum(LUDLEV®) for the Improvement of Fatty Liver Disease

Recruiting

📊 Sample Meta-Analyses

CRD42021231733

Systematic review and meta-analysis of the effect of Silybum Marianum supplementation on bodyweight in adults.

obesity

CRD42023424727

Effect of herbal medicine in the healing process of non-infected human skin wounds

Herbal medicine interventions for wound healing, investigate the effect and effi

📚 Sample References

PMID 33857761

Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum

Atherosclerosis · 2021

PMID 34630852

Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extract, Silymarin, and Silibinin via Modulation of Oxidative Stress, Apoptosis, Nrf2, PPAR γ, NF- κ B, and PI3K/Akt Signaling Pathways

Oxid Med Cell Longev · 2021

🌿 All Herb data fields for Silybum Marianum; Fruit of Silybum Marianum

🌿 Names

Pinyin Name

Shui Fei Ji

中文名 (Chinese)

水飞蓟

Latin Name

Silybi Fructus; Fructus Silybi

English Name

Silybum Marianum; Fruit of Silybum Marianum

Alias Names

水飞雉; 奶蓟; 老鼠簕

☯ TCM Properties

Properties (性味)

Bitter; Cool

Meridians (归经)

Liver; Gallbladder

Part Used

Achene

Therapeutic Class (EN)

Antipyretic Detoxicate Drugs

功效分类 (CN)

清热解毒药

🩺 Clinical Profile

Function (功能)

Clear heat and resolve toxinssoothe the liver and promote gallbladder function (i.e., bile secretion, etc.)

Indication (主治)

Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis.

🔗 External References

HERB DB

HERB005162 ↗

SymMap

379 ↗

TCMID

5134

TCMSP

379

TCM-ID

1987

🔍 Raw view — every non-empty column on this row (30 fields)

name

Silybum Marianum; Fruit of Silybum Marianum

chinese name

水飞蓟

pinyin name

Shui Fei Ji

latin name

Silybi Fructus; Fructus Silybi

english name

Silybum Marianum; Fruit of Silybum Marianum

properties english

Bitter; Cool

meridians english

Liver; Gallbladder

use part

Achene

symmap herb id

379

tcmid id

5134

tcmsp id

379

herb id str

HERB005162

function text

Clear heat and resolve toxinssoothe the liver and promote gallbladder function (i.e., bile secretion, etc.)

indication

Acute hepatitis, chronic hepatitis, cirrhosis, fatty liver, gallstones, cholangitis.

therapeutic en class

Antipyretic Detoxicate Drugs

therapeutic cn class

清热解毒药

tcm id id

1987

alias name

水飞雉; 奶蓟; 老鼠簕

📜 Related Formulas

7 · contains this herb

Shen Qi Gan Kang Capsule

Shen Qi Gan Kang Jiao Nang

Dangfei Liganning Capsule; Dang Fei Li Gan Ning Capsule

Dang Fei Li Gan Ning Jiao Nang

Compound Yi Gan Ling Capsule; Fufang Yiganling Capsule

Fufang Yiganling Jiaonang

Compound Yi Gan Ling Tablet

Fu Fang Yi Gan Ling Pian

Compound Dan Zhi Granule

Fu Fang Dan Zhi Ke Li

Yi Gan Ling Tablet

Yi Gan Ling Pian

Yi Gan Ling Capsule

Yi Gan Ling Jiao Nang

🏥 Linked Health Topics

1 · diseases via target pathways

Hepatitis C

syndrome

📋 Clinical Trials

2 · subject of clinical study

NCT01292161 Effects of Silybum Marianum on Treatment of Patients With Chronic Hepatitis C

→ Hepatitis C

NCT05913986 Supplementation With Alpha-lipoic Acid and Silybum Marianum(LUDLEV®) for the Imp

→ Metabolic Associated Fatty Liver Disease

📊 Meta-Analyses

2 · systematic review

CRD42021231733 Systematic review and meta-analysis of the effect of Silybum Marianum supplement

→ obesity

CRD42023424727 Effect of herbal medicine in the healing process of non-infected human skin woun

→ Herbal medicine interventions for wound healing, i

📚 PubMed References

2 · cited research

PMID 33857761 Triglyceride-induced cardiac lipotoxicity is mitigated by Silybum marianum

Atherosclerosis

PMID 34630852 Tackling of Renal Carcinogenesis in Wistar Rats by Silybum marianum Total Extrac

Oxid Med Cell Longev

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables