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Ingredient
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Gene Target
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Disease
30,170
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
⚗️ Ingredient
2-hydroxybenzoic acid
8
Clinical Trials
0
Meta-Analyses
0
PubMed References
Top Conditions Studied with 2-hydroxybenzoic acid
📋 Sample Trials
NCT00616239
Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate to Severe Melasma in Hispanic Women
Completed · Phase 4
NCT01914627
Parallel Group Trial to Evaluate the Efficacy and Safety of Loion® Compared to 10% Salicylic Acid in Patients With Chronic Psoriasis Capitis
Completed · Phase 2
NCT01976286
A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma
Active_Not_Recruiting
📊 Sample Meta-Analyses
None linked yet.
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for 2-hydroxybenzoic acid
⚗️ Identity
Name
2-hydroxybenzoic acid
Aliases / Synonyms
salicylic acid; 69-72-7; o-hydroxybenzoic acid; 2-Carboxyphenol; o-Carboxyphenol; Rutranex; Salonil; Retarder W; Duoplant
🧪 Chemistry
Molecular Weight
138.1220
LogP
1.0904
Drug-likeness
0.61
H-Bond Acceptors
2
H-Bond Donors
2
Rotatable Bonds
1
🔬 Structures
Canonical SMILES
C1=CC=C(C(=C1)C(=O)O)O
Isomeric SMILES
C1=CC=C(C(=C1)C(=O)O)O
InChIKey
YGSDEFSMJLZEOE-UHFFFAOYSA-N
InChI
InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
🔗 External References
HERB DB
PubChem CID
DrugBank
NPASS
NPC100551
HIT
C0383
TCMID
32991; 32990; 36205; 37061; 34445; 36518
🔍 Raw view — every non-empty column on this row (30 fields)
name
2-hydroxybenzoic acid
common names
salicylic acid; 69-72-7; o-hydroxybenzoic acid; 2-Carboxyphenol; o-Carboxyphenol; Rutranex; Salonil; Retarder W; Duoplant
herb ingredient id
HBIN005780
canonical smiles
C1=CC=C(C(=C1)C(=O)O)O
isomeric smiles
C1=CC=C(C(=C1)C(=O)O)O
inchi
InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
inchikey
YGSDEFSMJLZEOE-UHFFFAOYSA-N
mol wt
138.1220
num h acceptors
2
num h donors
2
mol logp
1.0904
num rotatable bonds
1
drug likeness
0.61
tcmid ingredient id
32991; 32990; 36205; 37061; 34445; 36518
pubchem cid
338
drugbank id
DB00936
npass id
NPC100551
hit id
C0383
🏥 Linked Health Topics
3 · studied for these conditions (text bridge)📋 Clinical Trials
8 · subject of clinical studyNCT00616239 Salicylic Acid Peels Combined With 4% Hydroquinone in the Treatment of Moderate
→ Melasma
NCT01914627 Parallel Group Trial to Evaluate the Efficacy and Safety of Loion® Compared to 1
→ Scalp Psoriasis
NCT01976286 A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Tr
→ Melanosis
NCT02352987 Effect of Neem Extract, Propylene Glycol and Salicylic Acid Combination in the T
→ Chronic Arsenic Poisoning
NCT00361322 Efficacy and Safety of a Preparation Containing an Antibiotic and Anti-Inflammat
→ Acne Vulgaris
NCT01446237 U0289-405: An Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of t
→ Acne Vulgaris
NCT05862441 A Study to Assess the Efficacy of Omnivirol-Salicylic Acid Combination Therapy f
→ Cutaneous Warts
NCT05779085 Efficacy of a Deep Cleansing Gel Containing 2% Salicylic Acid, 0.2% Zinc Glucona
→ Acne Vulgaris on the Face
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
empty — needs
HERB_herb_ingredientimport - Ingredient ↔ Target:
empty — needs
HERB_ingredient_targetimport - Target ↔ Disease:
empty — needs
HERB_target_diseaseimport - Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables