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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
🌿
Herb
6,826
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⚗️
Ingredient
44,595
→
🧬
Gene Target
15,505
→
🏥
Disease
30,170
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
🌿 Herb
Saffron
10
Clinical Trials
31
Meta-Analyses
8
PubMed References
Top Conditions Studied with Saffron
Depressive disorders, Alzheimer, Parkinson, sexual dysfuncti 2
According to the World Health Organization, 350 million peop 1
To investigate the effects of saffron supplementation on gly 1
Insomnia|Stress 1
diabetes mellitus. 1
-gynecology (dysmenorrhea, nausea pregnancy, climateric synd 1
There are more than 230 million people with diabetes worldwi 1
Diabetes Mellitus, Type 1|Diabetes type1 1
Diabetes mellitus (DM) is a group of endocrine metabolic dis 1
-Dementia (including Alzheimer's disease, vascular disease, 1
The Cochrane Schizophrenia Group 1
Ulcerative Colitis 1
📋 Sample Trials
NCT01625442
Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome
Completed · Phase 4
NCT04750681
Evaluation of the Effects of Saffron Extract on Sleep Quality and Stress
Completed
NCT04749576
Saffron as Anti Inflammatory Agent In Patients With Inflammatory Bowel Disease
Unknown
📊 Sample Meta-Analyses
CRD42020208426
Can phytotherapy present itself as a credible alternative to conventional treatments in current indications in general medicine? Systematic review of meta-analyzes
-gynecology (dysmenorrhea, nausea pregnancy, climateric syndrom) -rhumatology :
CRD42021268620
Comparative effects of nutraceuticals on body weight and waist circumference: a protocol for a network meta-analysis of randomised clinical trials
Effect of nutraceuticals on body weight and waist circumference in adults.
CRD42016047834
Systematic review of human clinical trials of Crocus Sativus (Saffron) in Alzheimer's Dementia
Alzheimer's dementia, Cognitive decline
📚 Sample References
PMID 30657284
Saffron inhibits the proliferation of hepatocellular carcinoma via inducing cell apoptosis
Panminerva Med · 2020
PMID 31797473
Effects of crocin and saffron aqueous extract on gene expression of SIRT1, AMPK, LOX1, NF-κB, and MCP-1 in patients with coronary artery disease: A randomized placebo-controlled clinical trial
Phytother Res · 2020
PMID 33015869
Effects of saffron supplementation on oxidative/antioxidant status and severity of disease in ulcerative colitis patients: A randomized, double-blind, placebo-controlled study
Phytother Res · 2021
🌿 All Herb data fields for Saffron
🌿 Names
Pinyin Name
Xi Hong Hua
中文名 (Chinese)
西红花
Latin Name
Croci Stigma; Stigma Croci
English Name
Saffron
☯ TCM Properties
Properties (性味)
Sweet; Calm
Meridians (归经)
Heart; Liver
Part Used
Stigma
Therapeutic Class (EN)
Blood Activating Stasis Removing Drugs
功效分类 (CN)
活血祛瘀药
🩺 Clinical Profile
Function (功能)
To activate blood circulation and eliminate blood stasis, to remove heat from blood and counteract toxicity, and to calm the nerves.
Indication (主治)
Treatment of amenrrhea with abdominal mass formation, blood stasis after childbirth, eruptions in infectious diseases, emotional dejection, mania.
🔗 External References
🔍 Raw view — every non-empty column on this row (29 fields)
name
Saffron
chinese name
西红花
pinyin name
Xi Hong Hua
latin name
Croci Stigma; Stigma Croci
english name
Saffron
properties english
Sweet; Calm
meridians english
Heart; Liver
use part
Stigma
symmap herb id
422
tcmid id
1784
tcmsp id
422
herb id str
HERB005826
function text
To activate blood circulation and eliminate blood stasis, to remove heat from blood and counteract toxicity, and to calm the nerves.
indication
Treatment of amenrrhea with abdominal mass formation, blood stasis after childbirth, eruptions in infectious diseases, emotional dejection, mania.
therapeutic en class
Blood Activating Stasis Removing Drugs
therapeutic cn class
活血祛瘀药
tcm id id
2226
📜 Related Formulas
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Shen Gui Lu Rong Wan
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Shen Chan Xiao Jie Jiao Nang
Dian She Pill
Dian She Wan
Dingkun Dan; Ding Kun Dan
Ding Kun Dan
Ershiwuwei Shanhu Pill; Er Shi Wu Wei Shan Hu Pill
Ershiwuwei Shanhu Wan
Er Shi Wu Wei Song Shi Pill; Ershiwuwei Songshi Pill
Ershiwuwei Songshi Wan
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Ershiwuwei Zhenzhu Wan
Feng Tong Pill
Feng Tong Wan
Er Shi Wei Shu Gan Capsule
Er Shi Wei Shu Gan Jiao Nang
Gao Xue Ya Su Jiang Pill
Gao Xue Ya Su Jiang Wan
Gan Chang Capsule
Gan Chang Jiao Nang
Hui Chun Medicated Wine
Hui Chun Jiu
Qi Shi Wei Zhen Zhu Pill; Qishiwei Zhenzhu Pill
Qishiwei Zhenzhu Wan
Renqing Changjue Pill; Ren Qing Chang Jue
Renqing Changjue
Renqing Mangjue Pill; Ren Qing Mang Jue
Renqing Mangjue
Liu Wei Xi Hong Hua Oral Liquid
Liu Wei Xi Hong Hua Kou Fu Ye
Nao Xin An Capsule
Nao Xin An Jiao Nang
Qi Shi Wei Song Shi Pill
Qi Shi Wei Song Shi Wan
San Shi Yi Wei Song Shi Pill
San Shi Yi Wei Song Shi Wan
🏥 Linked Health Topics
1 · studied for these conditions (text bridge)📋 Clinical Trials
10 · subject of clinical studyNCT01625442 Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syn
→ Metabolic Syndrome|Hypercholesterolemia|Hypertrigl
NCT04750681 Evaluation of the Effects of Saffron Extract on Sleep Quality and Stress
→ Insomnia|Stress
NCT04749576 Saffron as Anti Inflammatory Agent In Patients With Inflammatory Bowel Disease
→ Ulcerative Colitis
NCT01590485 Evaluation of the Effect of Saffron (Crocus Sativus) on Pain Control After Root
→ Post-treatment Pain Following Root Canal Therapy
NCT05572749 Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescent
→ PreDiabetes|Obesity|Dyslipidemias
NCT05484362 Acute Effect of Crocus Sativus on Postprandial Glycemia
→ Potential Abnormality of Glucose Tolerance|Appetit
NCT05690126 Effect of Saffron Extract Supplementation on Emotional Well-being Alterations
→ Mood Disturbance
NCT05696665 Role of Saffron and Chamomile in the Management of Parkinson's Disease
→ Parkinson Disease|Neurodegenerative Diseases
NCT05933460 Crocus Sativus Extract Impact in Metabolic Control of Patients With Diabetes Mel
→ Diabetes Mellitus, Type 1|Diabetes type1
NCT06138470 Evaluation of the Effect of a Combination of Plants to Regulate Mood
→ Mood Regulation
📊 Meta-Analyses
12 · systematic reviewCRD42020208426 Can phytotherapy present itself as a credible alternative to conventional treatm
→ -gynecology (dysmenorrhea, nausea pregnancy, clima
CRD42021268620 Comparative effects of nutraceuticals on body weight and waist circumference: a
→ Effect of nutraceuticals on body weight and waist
CRD42016047834 Systematic review of human clinical trials of Crocus Sativus (Saffron) in Alzhei
→ Alzheimer's dementia, Cognitive decline
CRD42017073130 Saffron (Crocus sativus) for the treatment of age-related macular degeneration:
→ Age-related macular degeneration.
CRD42018093026 The effect of saffron (crocus sativus) for mental illness: a systematic review a
→ Measures of mental disorders such as depression, l
CRD42018095378 The efficacy of saffron (Crocus sativus L.) for the treatment of mild to moderat
→ According to the World Health Organization, 350 mi
CRD42018096352 Saffron (adjunct) for people with schizophrenia who have antipsychotic-induced m
→ The Cochrane Schizophrenia Group
CRD42018115279 The effect of oral Crocus sativus L on anxiety and stress in humans: a systemati
→ Anxiety and psychological stress
CRD42019127560 Saffron for dementia and mild cognitive impairment: a systematic review and meta
→ -Dementia (including Alzheimer's disease, vascular
CRD42020159520 A systematic review of the effect of saffron extract on lipid profile in hyperli
CRD42020167865 Impact of saffron and its active compounds on glycemic and lipid control in pati
→ Type 2 diabetes mellitus is a chronic disease faci
CRD42020220274 Saffron for healthcare: an overview of meta-analyses and evidence mapping
→ Clinicians require a comprehensive overview of the
📚 PubMed References
8 · cited researchPMID 30657284 Saffron inhibits the proliferation of hepatocellular carcinoma via inducing cell
Panminerva Med
PMID 31797473 Effects of crocin and saffron aqueous extract on gene expression of SIRT1, AMPK,
Phytother Res
PMID 33015869 Effects of saffron supplementation on oxidative/antioxidant status and severity
Phytother Res
PMID 34165393 Therapeutic effects of saffron extract on different memory types, anxiety, and h
Nutr Neurosci
PMID 34194602 Total Flavonoids of Crocus sativus Petals Release tert-Butyl Hydroperoxide-Induc
Oxid Med Cell Longev
PMID 34956439 Intraperitoneal Lavage with Crocus sativus Prevents Postoperative-Induced Perito
Oxid Med Cell Longev
PMID 36126781 Saffron essential oil ameliorates CUMS-induced depression-like behavior in mice
J Ethnopharmacol
PMID 36482025 Flavonoid extract of saffron by-product alleviates hyperuricemia via inhibiting
Phytother Res
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
empty — needs
HERB_herb_ingredientimport - Ingredient ↔ Target:
empty — needs
HERB_ingredient_targetimport - Target ↔ Disease:
empty — needs
HERB_target_diseaseimport - Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables