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Relationship Graph Explorer

Follow the connections

Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

🌿
Herb
6,826
→
⚗️
Ingredient
44,595
→
🧬
Gene Target
15,505
→
🏥
Disease
30,170
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Abetalipoproteinemia Abortion, Habitual Agenesis Acanthamoeba Keratitis Acanthosis Nigricans Achondrogenesis Achondroplasia Acne Vulgaris Acne Keloid Apert Syndrome
🏥 Disease / Health Topic

Acute Heart Failure

Open on HERB 2.0 ↗
3
Clinical Trials
11
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT02544815
Digoxin Short Term Treatment Assessment Randomized Trial in AHF
Recruiting · Phase 3
NCT02135835
A Study to Evaluate the Efficacy and Safety of Shenfu Zhusheye in Patients With Acute Heart Failure
Completed · Phase 4
NCT05962255
Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decongestion in Acute Heart Failure
Completed · Phase 3
📊 Sample Meta-Analyses
CRD42020207805
Morphine Use in Acute Heart Failure Increase Adverse Outcomes: a meta-analysis of clinical trials
Studies examining the safety of morphine use for acute heart failure (AHF) have
CRD42021275008
Clinical Outcomes of Morphine Administration in Acute and Chronic Heart Failure: A Meta-Analysis
Morphine can be considered as a choice to relieve symptoms during heart failure
CRD42022344305
Metolazone vs. Vasopressin Antagonists as Adjuvant Diuretic Therapy in Heart Failure Exacerbation: A Systematic Review and Meta-Analysis of Outcomes
Acute heart failure exacerbation defined as a sudden or semi-gradual worsening o
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Acute Heart Failure
🏥 Names
Disease Name
Acute Heart Failure
Topic Type
syndrome
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Disease or Syndrome
MeSH Class
Cardiovascular Diseases
🔗 External References
HERB DB
HBDIS005697 ↗
DisGeNET
C0264714
🔍 Raw view — every non-empty column on this row (21 fields)
name
Acute Heart Failure
topic type
syndrome
disgenet disease type
disease
umls disease type
Disease or Syndrome
mesh disease class
Cardiovascular Diseases
umls disease type id
T047
mesh disease class id
C14
herb disease id
HBDIS005697
disgenet id
C0264714

🌿 Related Herbs

1 · shared evidence
Salt

⚗️ Related Ingredients

1 · shared evidence
Digoxin

📜 Related Formulas

1 · contains this herb
Shen Fu Injection

📋 Clinical Trials

3 · subject of clinical study
NCT02544815 Digoxin Short Term Treatment Assessment Randomized Trial in AHF
→ Acute Heart Failure
NCT02135835 A Study to Evaluate the Efficacy and Safety of Shenfu Zhusheye in Patients With
→ Acute Heart Failure
NCT05962255 Sodium Chloride vs. Glucose Solute as a Volume Replacement Therapy During Decong
→ Acute Heart Failure|Congestion|Heart Failure

📊 Meta-Analyses

11 · systematic review
CRD42020207805 Morphine Use in Acute Heart Failure Increase Adverse Outcomes: a meta-analysis o
→ Studies examining the safety of morphine use for a
CRD42021275008 Clinical Outcomes of Morphine Administration in Acute and Chronic Heart Failure:
→ Morphine can be considered as a choice to relieve
CRD42022344305 Metolazone vs. Vasopressin Antagonists as Adjuvant Diuretic Therapy in Heart Fai
→ Acute heart failure exacerbation defined as a sudd
CRD42022342524 Network meta-analysis of curative efficacy of Chinese medicine injection on Acut
→ Acute heart failure (AHF) is a group of complex cl
CRD42022342524 Network meta-analysis of curative efficacy of Chinese medicine injection on Acut
→ Acute heart failure (AHF) is a group of complex cl
CRD42021271686 Efficacy and safety of Shenmai injection in adjuvant treatment of acute heart fa
→ Acute heart failure is a clinical syndrome of acut
CRD42022327585 Curative efficacy of Shenmai injection on Acute heart failure: A protocol for sy
→ Acute heart failure
CRD42023448829 Reticular meta-analysis of different Chinese medicine injection combined with co
→ Acute heart failure is a common disease in clinica
CRD42023448829 Reticular meta-analysis of different Chinese medicine injection combined with co
→ Acute heart failure is a common disease in clinica
CRD42023448829 Reticular meta-analysis of different Chinese medicine injection combined with co
→ Acute heart failure is a common disease in clinica
CRD42023448829 Reticular meta-analysis of different Chinese medicine injection combined with co
→ Acute heart failure is a common disease in clinica
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables