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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Herb
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Ingredient
44,595
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Gene Target
15,505
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🏥
Disease
30,170
→
🧪
Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
Quick picks: Abetalipoproteinemia Abortion, Habitual Agenesis Acanthamoeba Keratitis Acanthosis Nigricans Achondrogenesis Achondroplasia Acne Vulgaris Acne Keloid Apert Syndrome
🏥 Disease / Health Topic

Subclinical Hypothyroidism

Open on HERB 2.0 ↗
9
Clinical Trials
14
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT00498238
The Effect of Levothyroxine on Arterial Stiffness and Lipid Profile in Patients With Subclinical Hypothyroidism
Completed
NCT02090907
Effects of Levothyroxine on Endothelial Function of Patients With Subclinical Hypothyroidism
Completed · Phase 2|Phase 3
NCT04288115
Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism
Completed · Phase 4
📊 Sample Meta-Analyses
CRD42017079808
The impact of levothyroxine therapy in pregnant women with subclinical hypothyroidism on obstetrical and childhood outcomes: systematic review and meta-analysis of randomized controlled trials
Subclinical hypothyroidism in pregnancy.
CRD42018089578
Effectiveness of levothyroxine therapy on pregnancy outcomes in women with subclinical hypothyroidism: systematic review and meta-analysis of RCTs
Levothyroxine therapy Levothyroxine therapy for subclinical hypothyroidism
CRD42018093138
Effect of levothyroxine on blood pressure in patients with subclinical hypothyroidism: a systematic review and meta-analysis
Subclinical hypothyroidism (SCH) is a state with elevated serum thyrotropin leve
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Subclinical Hypothyroidism
🏥 Names
Disease Name
Subclinical Hypothyroidism
Topic Type
syndrome
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Disease or Syndrome
MeSH Class
Endocrine System Diseases
🔗 External References
HERB DB
HBDIS006666 ↗
DisGeNET
C0271790
🔍 Raw view — every non-empty column on this row (21 fields)
name
Subclinical Hypothyroidism
topic type
syndrome
disgenet disease type
disease
umls disease type
Disease or Syndrome
mesh disease class
Endocrine System Diseases
umls disease type id
T047
mesh disease class id
C19
herb disease id
HBDIS006666
disgenet id
C0271790

⚗️ Related Ingredients

3 · shared evidence
3,5,3',5'-tetraiodothyronine
3,5,3'-triiodothyronine
Femara

📋 Clinical Trials

9 · subject of clinical study
NCT00498238 The Effect of Levothyroxine on Arterial Stiffness and Lipid Profile in Patients
→ Subclinical Hypothyroidism
NCT02090907 Effects of Levothyroxine on Endothelial Function of Patients With Subclinical Hy
→ Subclinical Hypothyroidism
NCT04288115 Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyro
→ Subclinical Hypothyroidism
NCT00388297 Thyroid Therapy for Mild Thyroid Deficiency in Pregnancy
→ Subclinical Hypothyroidism|Hypothyroxinemia|Pregna
NCT00921050 Subclinical Hypothyroidism and Mind in the Elderly
→ Subclinical Hypothyroidism
NCT01832753 Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
→ Down Syndrome|Subclinical Hypothyroidism
NCT02399475 Mechanistic Study of Subclinical Hypothyroidism In the Elderly
→ Subclinical Hypothyroidism
NCT02399475 Mechanistic Study of Subclinical Hypothyroidism In the Elderly
→ Subclinical Hypothyroidism
NCT06041204 Best Treatment for Women With Both (Polycystic Ovary Syndrome) PCOS and Subclini
→ PCOS (Polycystic Ovary Syndrome) of Bilateral Ovar

📊 Meta-Analyses

12 · systematic review
CRD42017079808 The impact of levothyroxine therapy in pregnant women with subclinical hypothyro
→ Subclinical hypothyroidism in pregnancy.
CRD42018089578 Effectiveness of levothyroxine therapy on pregnancy outcomes in women with subcl
→ Levothyroxine therapy Levothyroxine therapy for su
CRD42018093138 Effect of levothyroxine on blood pressure in patients with subclinical hypothyro
→ Subclinical hypothyroidism (SCH) is a state with e
CRD42018106182 Effect of levothyroxine on improvement in endothelial dysfunction in subclinical
→ Subclinical hypothyroidism
CRD42020168962 Pregnancy and Neonatal Outcomes With Levothyroxine Treatment in Women With Subcl
→ Levothyroxine treatment for subclinical hypothyroi
CRD42022296723 Levothyroxine treatment and pregnancy outcomes in women with subclinical hypothy
→ Subclinical hypothyroidism (SCH) is the most commo
CRD42022308006 Cardiovascular and bone health consequences of prescribing levothyroxine in the
→ Hypothyroidism is a common chronic disease caused
CRD42022321937 Clinical benefits of levothyroxine in women with subclinical hypothyroidism duri
→ Subclinical hypothyroidism is a common thyroid dis
CRD42022363801 Systematic Review and Meta-Analysis of Levothyroxine Effect on Blood Pressure in
→ Subclinical hypothyroidism (SCH) is a biochemical
CRD42023390228 Effects of levothyroxine therapy on bone metabolism in hypothyroidism patients:
→ Hypothyroidism, comprising both subclinical hypoth
CRD42021254451 A CompaRative Meta-Analysis of Treating Autoimmune Thyroiditis Using Vitamin D,
→ Autoimmune thyroiditis (AIT) is the most frequent
CRD42021254451 A CompaRative Meta-Analysis of Treating Autoimmune Thyroiditis Using Vitamin D,
→ Autoimmune thyroiditis (AIT) is the most frequent
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: empty — needs HERB_herb_ingredient import
  • Ingredient ↔ Target: empty — needs HERB_ingredient_target import
  • Target ↔ Disease: empty — needs HERB_target_disease import
  • Herb → Target → Disease (full chemical spine): awaiting Phase 2e link tables