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trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases
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⚗️ Ingredient

4-methylpyrazole

Open on HERB 2.0 ↗
1
Clinical Trials
1
Meta-Analyses
0
PubMed References
Top Conditions Studied with 4-methylpyrazole
Severe acetaminophen (paracetamol) poisoning 1 Acetaminophen|Drug Overdose|Acetaminophen Overdose|Acetamino 1
📋 Sample Trials
NCT05517668
Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose
Recruiting · Phase 2
📊 Sample Meta-Analyses
CRD42020156946
Cimetidine, fomepizole, or calmangafodipir in patients with acetaminophen (paracetamol) poisoning treated with IV N-acetylcysteine.
Severe acetaminophen (paracetamol) poisoning
📚 Sample References
None linked yet.
⚗️ All Ingredient data fields for 4-methylpyrazole
⚗️ Identity
Name
4-methylpyrazole
Aliases / Synonyms
fomepizole; 4-Methyl-1H-pyrazole; 7554-65-6; Antizol; 1H-Pyrazole, 4-methyl-; 4-Methylpyrazol; Fomepizol; Fomepizolum; Fomepizol [INN-Spanish]
🧪 Chemistry
Molecular Weight
82.1060
LogP
0.7181
Drug-likeness
0.49
H-Bond Acceptors
1
H-Bond Donors
1
🔬 Structures
Canonical SMILES
CC1=CNN=C1
Isomeric SMILES
CC1=CNN=C1
InChIKey
RIKMMFOAQPJVMX-UHFFFAOYSA-N
InChI
InChI=1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)
🔗 External References
HERB DB
HBIN010717 ↗
PubChem CID
3406 ↗
NPASS
NPC15826
HIT
C0082
TCMID
35252
🔍 Raw view — every non-empty column on this row (29 fields)
name
4-methylpyrazole
common names
fomepizole; 4-Methyl-1H-pyrazole; 7554-65-6; Antizol; 1H-Pyrazole, 4-methyl-; 4-Methylpyrazol; Fomepizol; Fomepizolum; Fomepizol [INN-Spanish]
herb ingredient id
HBIN010717
canonical smiles
CC1=CNN=C1
isomeric smiles
CC1=CNN=C1
inchi
InChI=1S/C4H6N2/c1-4-2-5-6-3-4/h2-3H,1H3,(H,5,6)
inchikey
RIKMMFOAQPJVMX-UHFFFAOYSA-N
mol wt
82.1060
num h acceptors
1
num h donors
1
mol logp
0.7181
num rotatable bonds
0
drug likeness
0.49
tcmid ingredient id
35252
pubchem cid
3406
npass id
NPC15826
hit id
C0082

📋 Clinical Trials

1 · subject of clinical study
NCT05517668 Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overd
→ Acetaminophen|Drug Overdose|Acetaminophen Overdose

📊 Meta-Analyses

1 · systematic review
CRD42020156946 Cimetidine, fomepizole, or calmangafodipir in patients with acetaminophen (parac
→ Severe acetaminophen (paracetamol) poisoning
How relationships are computed
  • Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
  • Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
  • Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
  • Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
  • Target ↔ Disease: ACTIVE — direct link via target_health_topics
  • Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables