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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.
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Ingredient
44,598
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Gene Target
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Disease
30,467
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Evidence
23,295
trials · metas · refs
Plus 6,743 TCM formulas connecting herbs together
21 Diseases matching "Depressive Disorder"
Depressive Disorder
Depressive Disorder, Major
Depressive Disorder, Treatment-Resistant
Melancholia
Mental Depression
Depressive Syndrome
Unipolar Depression
Depression, Neurotic
Endogenous Depression
Psychosis, Involutional
Involutional Depression
Involutional Paraphrenia
Major Depressive Disorder
Seasonal Affective Disorder
Atypical Depressive Disorder
Recurrent Depressive Disorder
Persistent Depressive Disorder
Major Depression, Single Episode
Recurrent Major Depressive Episodes
Mixed Anxiety And Depressive Disorder
Major Depressive Disorder, Increased Recurrence of
🏥 Disease / Health Topic
Depressive Disorder
28
Clinical Trials
23
Meta-Analyses
0
PubMed References
📋 Sample Trials
NCT01496248
Efficacy Study of Korean Red Ginseng to Treat Depression
Completed
NCT00421369
Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T3)and Reboxetine: Clinical Efficacy, Adverse Effects and Predictors of Response.
Completed
NCT00186264
Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response?
Completed
📊 Sample Meta-Analyses
CRD42021268446
The neuropsychotropic effects of Crocus sativus L. (saffron): an overview of systematic review investigating its efficacy in the treatment of neurological and psychiatric disorders
Depressive disorders, Alzheimer, Parkinson, sexual dysfunction, anxiety disorder
CRD42022308316
Crocus sativus for insomnia in adults: a systematic review and meta-analysis
Depressive disorders, Alzheimer, Parkinson, sexual dysfunction, anxiety disorder
CRD42021265946
Monoamines and Kynurenine pathway metabolites in Cerebrospinal Fluid for depression: a systematic review
Major depressive disorder (MDD) is one of the most important causes of disabilit
📚 Sample References
None linked yet.
🏥 All Disease / Health Topic data fields for Depressive Disorder
🏥 Names
Disease Name
Depressive Disorder
Alias Names
Depression, Neurotic; Depressive Syndrome; Dysthymic Disorder; Neurotic Disorder; Depressivity; Depression; Melancholia; Major Depressive Disorder; Unipolar Depression; Disorder, Depressive; Endogenous Depression; Depression, Endogenous; Mental Depression; Depressive Disorder
Topic Type
disease
🧬 Ontology Classifications
DisGeNET Type
disease
UMLS Type
Mental or Behavioral Dysfunction
MeSH Class
Mental Disorders
HPO Class
Abnormality of the nervous system
DO Class
disease of mental health
🔗 External References
HERB DB
MeSH
HPO
Disease Ontology
1596; 2848; 1470; 12139; 4964; 1
DisGeNET
C0011581
🔍 Raw view — every non-empty column on this row (29 fields)
name
Depressive Disorder
alias name
Depression, Neurotic; Depressive Syndrome; Dysthymic Disorder; Neurotic Disorder; Depressivity; Depression; Melancholia; Major Depressive Disorder; Unipolar Depression; Disorder, Depressive; Endogenous Depression; Depression, Endogenous; Mental Depression; Depressive Disorder
topic type
disease
disgenet disease type
disease
umls disease type
Mental or Behavioral Dysfunction
mesh disease class
Mental Disorders
hpo disease class
Abnormality of the nervous system
do disease class
disease of mental health
umls disease type id
T048
mesh disease class id
F03
hpo disease class id
HP:0000707
do disease class id
DOID:150
herb disease id
HBDIS000756
disgenet id
C0011581
mesh id
D003866
hpo id
HP:0000716
do id
1596; 2848; 1470; 12139; 4964; 1
🌿 Related Herbs
1 · contains this compound⚗️ Related Ingredients
12 · compounds in this herb📜 Related Formulas
1 · contains this herb📋 Clinical Trials
12 · subject of clinical studyNCT01496248 Efficacy Study of Korean Red Ginseng to Treat Depression
→ Major Depressive Disorder
NCT00421369 Augmentation of the Antidepressant Action of Sertraline With Triiodothyronine (T
→ Major Depressive Disorder
NCT00186264 Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response
→ Depressive Disorder, Major
NCT01263119 A Study of LY2216684 and Warfarin in Healthy Subjects
→ Major Depressive Disorder
NCT01022632 Effect of Curcumin as Nutraceutical in Patients of Depression
→ Major Depressive Disorder
NCT01266590 A Study of LY2216684 and Digoxin in Healthy Subjects
→ Major Depressive Disorder
NCT00705003 Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and
→ Major Depressive Disorder
NCT02346539 Effect of Nicotine on Brain Reward Pathways
→ Depressive Disorder
NCT01409096 Study Using Pregnenolone to Treat Bipolar Depression
→ Bipolar Disorder|Major Depressive Disorder
NCT03645096 Development of Pregnenolone as a Treatment for Depression
→ Major Depressive Disorder
NCT00977353 N-methylglycine (Sarcosine) Treatment for Depression
→ Major Depressive Disorder|Depression|Major Depress
NCT04975100 Evaluation of Efficacy and Safety of add-on Sarcosine in Patients With Major Dep
→ Major Depressive Disorder
📊 Meta-Analyses
12 · systematic reviewCRD42021268446 The neuropsychotropic effects of Crocus sativus L. (saffron): an overview of sys
→ Depressive disorders, Alzheimer, Parkinson, sexual
CRD42022308316 Crocus sativus for insomnia in adults: a systematic review and meta-analysis
→ Depressive disorders, Alzheimer, Parkinson, sexual
CRD42021265946 Monoamines and Kynurenine pathway metabolites in Cerebrospinal Fluid for depress
→ Major depressive disorder (MDD) is one of the most
CRD42019119766 Cannabidiol as a treatment for mood disorders: a systematic review
→ Mood disorders (Depressive disorders or Bipolar di
CRD42015025056 Clinical effects of curcumin on depression: a systematic review and meta-analysi
→ Depression or depressive disorder.
CRD42015025203 The role of curcumin in patients with major depressive disorders: a mini meta-an
→ Major Depressive Disorders (MDD) is a serious clin
CRD42015024796 Huperzine A for major depressive disorder: a review of the literature
→ Huperzine A, an alkaloid initially identified from
CRD42015024796 Huperzine A for major depressive disorder: a review of the literature
→ Huperzine A, an alkaloid initially identified from
CRD42015024796 Huperzine A for major depressive disorder: a review of the literature
→ Huperzine A, an alkaloid initially identified from
CRD42020143432 Lithium and suicide prevention in mood disorders and in the general population:
→ Bipolar disorder, Major Depressive Disorder, Schiz
CRD42018115782 The association between the consumption of free sugar and depression: a meta-ana
→ Depression, having depressive symptoms and depress
CRD42018108273 Association of serum testosterone concentration with depression in men: a system
→ Depression or Depressive disorder. Testosterone co
How relationships are computed
- Clinical Trials / Meta-Analyses / References: direct foreign-key link via
subject_entity_id(Phase 2d wireup) - Formula ↔ Herbs: text bridge via
formulas.herbs_in_pinyinmatchingherbs.pinyin_name - Herb ↔ Ingredient:
ACTIVE — direct link via
herb_ingredients - Ingredient ↔ Target:
ACTIVE — direct link via
ingredient_targets - Target ↔ Disease:
ACTIVE — direct link via
target_health_topics - Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables