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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

28 Diseases matching "heart failure"

Heart Failure Heart Failure, Systolic Heart Failure, Diastolic Heart Failure, Right-Sided Heart Failure Nyha Class Ii Heart Failure With Normal Ejection Fraction Heart Failure With Reduced Ejection Fraction [Hfre Heart Failure With Preserved Ejection Fraction [Hf Myocardial Failure Acute Heart Failure Fetal Heart Failure Heart Decompensation Chronic Heart Failure Stage D Heart Failure Refractory Heart Failure Left-Sided Heart Failure Congestive Heart Failure Right Ventricular Failure High Output Heart Failure Hypertensive Heart Failure Acute Congestive Heart Failure Acute Left-Sided Heart Failure Chronic Systolic Heart Failure Chronic Congestive Heart Failure Low-Output Congestive Heart Failure High-Output Congestive Heart Failure Biventricular Congestive Heart Failure Mental Retardation, X-Linked, Syndromic 32

🏥 Disease / Health Topic

Heart Failure

Open on HERB 2.0 ↗

Clinical Trials

171

Meta-Analyses

PubMed References

📋 Sample Trials

NCT05589428

Low-salt Bread in Heart Failure, Pilot Study

Completed

NCT01481402

Liothyronine and Heart Failure. The Long Term Effect of Liothyronine on Left Ventricular Ejection Fraction (LVEF)

Completed

NCT04705987

Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients With Acutely Decompensated Heart Failure

Completed · Phase 3

📊 Sample Meta-Analyses

CRD42021244209

The efficacy and safety of Ginkgo Biloba Dropping Pills in the treatment of coronary heart disease angina: a systematic review and meta-analysis

Systematic evaluation of the Ginkgo Biloba Dropping Pills on coronary heart dise

CRD42020141825

Combined therapy of hypertensive nephropathy with ginkgo leaf extract and dipyridamole injection and antihypertensive drugs: a systematic review and meta-analysis

Hypertension is a risk factor for stroke, coronary artery disease, heart failure

CRD42021272199

The association of garlic intake and cardiovascular risk factors

Cardiovascular diseases (CVDs) are the major cause of death worldwide. The term

📚 Sample References

None linked yet.

🏥 All Disease / Health Topic data fields for Heart Failure

🏥 Names

Disease Name

Heart Failure

Alias Names

Chf; Left-Sided Heart Failure; Cardiac Insufficiency; Heart Failure; Heart Failure, Right-Sided; Heart Decompensation; Cardiac Failure; Congestive Heart Failure; Heart Failure, Congestive; Myocardial Failure; Cardiac Failures; Heart Failure, Unspecified; Chronic Heart Failure

Topic Type

syndrome

🧬 Ontology Classifications

DisGeNET Type

disease

UMLS Type

Disease or Syndrome

MeSH Class

Cardiovascular Diseases

HPO Class

Abnormality of the cardiovascular system

DO Class

disease of anatomical entity

🔗 External References

HERB DB

MeSH

ICD-10

HPO

Disease Ontology

6000

DisGeNET

C0018801

🔍 Raw view — every non-empty column on this row (31 fields)

name

Heart Failure

alias name

topic type

syndrome

disgenet disease type

disease

umls disease type

Disease or Syndrome

mesh disease class

Cardiovascular Diseases

hpo disease class

Abnormality of the cardiovascular system

do disease class

disease of anatomical entity

umls disease type id

T047

mesh disease class id

C14

hpo disease class id

HP:0001626

do disease class id

DOID:7

herb disease id

HBDIS001264

disgenet id

C0018801

mesh id

D006333

hpo id

HP:0001635

do id

6000

icd10 id

I50.9; I50

tcmsp disease id

353

🌿 Related Herbs

1 · contains this compound

Ephedra

Ma Huang

⚗️ Related Ingredients

11 · compounds in this herb

🧬 Gene / Protein Targets

4 · genes implicated in this disease

CAT

Gene CAT

TNF

Gene TNF

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, gamma isoform

Alpha-2A adrenergic receptor

📜 Related Formulas

1 · contains this herb

Shen Fu Injection

📋 Clinical Trials

12 · subject of clinical study

NCT05589428 Low-salt Bread in Heart Failure, Pilot Study

→ Heart Failure, Systolic|Sodium Imbalance|Food Sele

NCT01481402 Liothyronine and Heart Failure. The Long Term Effect of Liothyronine on Left Ven

→ Heart Failure|Low T3 Syndrome

NCT04705987 Randomized Double-blind Trial to Study the Benefit of Colchicine in Patients Wit

→ HEART FAILURE

NCT00007683 Warfarin and Antiplatelet Therapy in Chronic Heart Failure

→ Heart Failure

NCT01005602 Digoxin Dosing in Heart Failure: A Simplified Nomogram Versus Standard Care

→ Heart Failure

NCT01398371 Digoxin Withdrawal in Stable Heart Failure

→ Heart Failure

NCT01796093 Digoxin Versus Ivabradine in Heart Failure With Preserved Systolic Function

→ Heart Failure|Atrial Fibrillation

NCT02544815 Digoxin Short Term Treatment Assessment Randomized Trial in AHF

→ Acute Heart Failure

NCT03783429 Digoxin Evaluation in Chronic Heart Failure: Investigational Study In Outpatient

→ Heart Failure

NCT00550121 Does Ascorbic Acid Reduce Sympathoexcitation in CHF?

→ Heart Failure

NCT04036110 Vitamin C Supplementation Intervention

→ Heart Failure

NCT01901809 Diuretics and Dopamine in Heart Failure With Preserved Ejection Fraction

→ Heart Failure, Diastolic

📊 Meta-Analyses

12 · systematic review

CRD42021244209 The efficacy and safety of Ginkgo Biloba Dropping Pills in the treatment of coro

→ Systematic evaluation of the Ginkgo Biloba Droppin

CRD42020141825 Combined therapy of hypertensive nephropathy with ginkgo leaf extract and dipyri

→ Hypertension is a risk factor for stroke, coronary

CRD42021272199 The association of garlic intake and cardiovascular risk factors

→ Cardiovascular diseases (CVDs) are the major cause

CRD42022312909 Add-on effect of Red ginseng-containing Chinese herbal medicine for heart failur

→ Heart failure with preserved ejection fraction (HF

CRD42020188241 Efficacy and safety of Ginseng decoction on the treatment of heart failure as co

→ heart failure (HF) is a progressive syndrome that

CRD42021267742 Meta-analysis of ginseng on the treatment of acute decompensated heart failure

→ Acute decompensated heart failure (ADHF) accounts

CRD42021259878 Effects of long-term cocoa consumption on cardiovascular health outcomes in olde

→ Cocoa/chocolate consumption in older adults aged 6

CRD42020209883 Systematic review and meta-analysis of the effect of uric acid lowering treatmen

→ Heart Failure and Hyperuricemia. Serum uric acid,

CRD42016053009 Efficacy of milrinone over dobutamine in heterogeneous population of critically

→ Severe heart failure, Cardiogenic shock, Low cardi

CRD42021256586 Effect of aldosterone antagonists on outcomes and cardiac function in patients w

→ Heart failure (HF) is a severe clinical syndrome t

CRD42016049846 Efficacy of vitamin D supplementation in chronic heart failure among adults: an

→ Chronic heart failure (CHF).

CRD42018100883 Utility of computed tomographic coronary angiography and coronary artery calcium

→ Perioperative cardiovascular complications includi

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables