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Oyster

Oyster mushroom (Pleurotus ostreatus) is a food mushroom. What small human meal trials found, what is not known, and the spore-allergy reports that matter for people who work with it.

Content last updated . This page has not been medically reviewed.

Close-up of oyster

Safety first. Supplements can cause side effects and interact with medicines. Read mushroom safety and interactions before you use any mushroom product.

Documented analytical data

Each group below is one study's measurement of the stated specimen or preparation. It is not a typical value for the species or product, varies between specimens, and says nothing about effects or safety. 35 values from 5 sources.

Chen SY, et al. Contents of lovastatin, gamma-aminobutyric acid and ergothioneine in mushroom fruiting bodies and myc... (3 values)

Source: Chen SY, et al. Contents of lovastatin, gamma-aminobutyric acid and ergothioneine in mushroom fruiting bodies and mycelia. LWT - Food Science and Technology 2012. doi:10.1016/j.lwt.2012.01.019. Abstract read via Europe PMC. Laboratory: not stated in the text read. Method: HPLC (as described in abstract). Date: not stated in the text read.

Measured values
Specimen or preparationAnalyteValueWhat it isSample size and scope
Pleurotus ostreatus, Japan-sourced sampleLovastatin606.5 mg per kg (freeze-dried fruiting body (as described in the abstract))mean (reported)not stated in abstract. single published study
Pleurotus ostreatus, Korea-sourced sampleErgothioneine1829.4 mg per kg (fruiting body, dry basis (as described in the abstract))mean (reported)not stated in abstract. single published study
Pleurotus ostreatus, Taiwan-sourced sampleErgothioneine1458.4 mg per kg (fruiting body, dry basis (as described in the abstract))mean (reported)not stated in abstract. single published study
Lam YS, Okello EJ. Determination of Lovastatin, beta-glucan, Total Polyphenols, and Antioxidant Activity in Raw and P... (2 values)

Source: Lam YS, Okello EJ. Determination of Lovastatin, beta-glucan, Total Polyphenols, and Antioxidant Activity in Raw and Processed Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus. International Journal of Medicinal Mushrooms 2015;17(2). doi:10.1615/intjmedmushrooms.v17.i2.30. Abstract read via... Laboratory: not stated in the text read. Method: varies by row (see source). Date: not stated in the text read.

Measured values
Specimen or preparationAnalyteValueWhat it isSample size and scope
Pleurotus ostreatus, rawBeta-glucan23.9 percent of dry matter (dry matter, raw fruiting body (dry matter content 8 percent))mean (reported)not stated in abstract. single published study
Pleurotus ostreatus, rawTotal polyphenols487.12 mg gallic acid equivalents per 100 g dry matter (dry matter, raw fruiting body)mean (reported)not stated in abstract. single published study
Tsiantas K, et al. On the Identification and Quantification of Ergothioneine and Lovastatin in Various Mushroom Speci... (2 values)

Source: Tsiantas K, et al. On the Identification and Quantification of Ergothioneine and Lovastatin in Various Mushroom Species. Molecules 2021;26(7):1832. doi:10.3390/molecules26071832. Table 3. Open access (PMC8036957). Laboratory: not stated in the text read. Method: varies by row (see source). Date: not stated in the text read.

Measured values
Specimen or preparationAnalyteValueWhat it isSample size and scope
Pleurotus ostreatus grown on wheat strawErgothioneine607.3 mg per kg dry sample (dry weight, fruiting body)mean (reported)3 (mean +/- standard error 11.2). single published study
Pleurotus ostreatus grown on wheat strawLovastatin1.11 mg per kg dry sample (dry weight, fruiting body)mean (reported)3 (mean +/- standard error 0.042). single published study
U.S. Department of Agriculture. FoodData Central, SR Legacy, FDC ID 168580, Mushrooms, oyster, raw. https://fdc.nal.u... (12 values)

Source: U.S. Department of Agriculture. FoodData Central, SR Legacy, FDC ID 168580, Mushrooms, oyster, raw. https://fdc.nal.usda.gov/fdc-app.html#/food-details/168580/nutrients. Public domain. Laboratory: USDA Nutrient Data Laboratory. Method: as in USDA record. Date: SR Legacy 2018.

Measured values
Specimen or preparationAnalyteValueWhat it isSample size and scope
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Choline, total48.7 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Copper0.244 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Dietary fibre, total2.3 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Energy139 kJ per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Folate, total38 ug per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Niacin4.956 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Pantothenic acid1.294 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Potassium420 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Protein3.31 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Riboflavin0.349 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Selenium2.6 ug per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA SR Legacy FDC 168580)Vitamin D2 (ergocalciferol)0.7 ug per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
U.S. Department of Agriculture. FoodData Central, Foundation Foods, FDC ID 1999627, Mushroom, oyster. https://fdc.nal... (16 values)

Source: U.S. Department of Agriculture. FoodData Central, Foundation Foods, FDC ID 1999627, Mushroom, oyster. https://fdc.nal.usda.gov/fdc-app.html#/food-details/1999627/nutrients. Public domain. Laboratory: USDA Nutrient Data Laboratory. Method: as in USDA record. Date: Foundation Foods 2021-10-28 record.

Measured values
Specimen or preparationAnalyteValueWhat it isSample size and scope
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Beta-glucan1.92 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Carbohydrate, by difference6.94125 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Copper0.1064 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Dietary fibre, total2.85 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Energy (Atwater specific factors)33.31965 kcal per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Ergosterol58.49 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Ergothioneine14 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Folate, total63.14 ug per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Glutathione17.5 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Niacin5.751 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Potassium281.6 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Protein2.89875 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Riboflavin0.2438 mg per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Selenium1.379 ug per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Total fat0.1875 g per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Oyster mushroom, raw (USDA Foundation Foods FDC 1999627)Vitamin D2 (ergocalciferol)0.04063 ug per 100 g (fresh, raw, edible portion (UV exposure not stated))mean (reported)see FDC record. USDA analytical mean of the sampled foods
Water-soluble vitaminPleurotus ostreatus

What is Oyster mushroom good for?

What the body uses it for, and how strong the evidence is. A normal job in the body is not proof that extra supplements add benefit; each card says which.

As a food (nutrition)

Preliminary or mixed

Oyster mushroom is a low-calorie food with some protein and fibre, plus B vitamins, potassium and copper. USDA lists 33 kcal, 2.9 g protein and 2.85 g fibre per 100 g raw.

Supplements: This applies to eating the mushroom. We found no evidence that extra supplements add a benefit over a normal diet.

Ergothioneine from food

Lab or animal research only

Mushrooms are among the richer food sources of ergothioneine, a dietary antioxidant. USDA lists 14 mg per 100 g raw oyster mushroom.

Supplements: Supplement benefit not shown; the older-adult trials used the whole mushroom, not ergothioneine extracts.

Pleuran beta-glucan and children's respiratory infections

Preliminary or mixed

Pleuran, a beta-glucan purified from Pleurotus ostreatus, was tested in several trials in children with frequent respiratory infections, with fewer infections reported in some. The trials used purified products with added vitamins or minerals, not the mushroom.

Supplements: Specific to purified pleuran products in children; it does not show that oyster mushroom as food or powder has the same effect.

Beta-glucan fibre and a meal's gut hormones

Preliminary or mixed

In 22 adults with impaired glucose tolerance, a meal with 20 g of oyster mushroom powder did not change blood sugar or insulin but changed fatty acids and GLP-1 after the meal.

Supplements: Applies to a dried powder in a meal in one small crossover trial.

Memory and mood in healthy older adults

Preliminary or mixed

A 12-week trial in 80 adults aged 60 to 80 found better delayed word recall and less negative mood with four oyster portions a week than placebo; a single-meal trial was mixed.

Supplements: Food-portion trial, not a supplement; not shown for people with memory loss.

Heart and metabolic risk factors

Not enough evidence

A systematic review found limited evidence for mushrooms and heart risk markers and rated most articles poor; one 8-week trial mixed button and oyster mushrooms.

Supplements: No supplement benefit shown.

Lovastatin traces

Not enough evidence

Lovastatin, a statin-type compound, has been reported in oyster mushroom, but measured amounts range from not detected to about 600 mg per kg dry weight depending on study and method.

Supplements: No evidence of a cholesterol effect from eating or supplementing.

Connected topics

Open a group to see how each topic connects and how strong the evidence is.

Health goals (2)
  • Immune SupportPreliminary or mixed

    Purified pleuran from this mushroom was linked to fewer respiratory infections in some trials in children. This does not show the same for eating the mushroom.

  • Memory SupportPreliminary or mixed

    One 12-week trial in healthy older adults found better delayed word recall with four oyster portions a week; a single-meal trial was mixed.

Body systems (3)
  • Immune SupportPreliminary or mixed

    Pleuran trials in children reported fewer infections and immune-marker changes with a purified extract; not shown for the mushroom itself.

  • Immune SystemPreliminary or mixed

    Same evidence as for immune support: purified pleuran, children, mostly one research group.

  • Respiratory HealthPreliminary or mixed

    Pleuran products were tested for infections and asthma control in children; results are from abstracts of trials by one group and concern purified products.

Body parts (2)
  • LungsDocumented risk

    Spores can cause asthma and anaphylaxis in people who grow, pack or sell oyster mushroom (case reports).

  • Immune SystemPreliminary or mixed

    Pleuran trials in children; purified extract, limited evidence.

Functional actions (2)
  • AntioxidantLab or animal research only

    Ergothioneine and polyphenols were measured in oyster mushroom and act as antioxidants in the lab; no human benefit outcome shown.

  • Immune ModulationPreliminary or mixed

    Pleuran, a beta-glucan from this species, changed immune measures and infection counts in children's trials; not shown for the whole mushroom.

Root causes (1)
  • Heavy Metal ExposureDocumented risk

    Pleurotus ostreatus concentrated cadmium and mercury added to its growing medium in a laboratory study, so growing material and testing matter.

Conditions & symptoms (4)
  • Asthma, OccupationalDocumented risk

    Case reports link asthma to spores of this mushroom in people who grow or sell it.

  • AnaphylaxisDocumented risk

    One case report describes anaphylaxis after inhaling oyster mushroom spores on a farm.

  • Childhood AsthmaPreliminary or mixed

    One trial in 230 children with partly controlled asthma found better asthma control in under-12s and fewer infections in over-12s with a pleuran product; abstract only.

  • Trials in children tested purified pleuran products for fewer infections; results positive in some, from one research group, using purified products with vitamins or minerals.

Documented risks and interactions (2)
  • Spore allergy and work-related asthma. Spores of Pleurotus ostreatus can cause asthma and anaphylaxis in people who grow, pack or sell it. These are case reports.
  • Metal uptake from growing material. Pleurotus ostreatus concentrated added cadmium and mercury in a laboratory growing study, so the growing material and product testing matter.

Explore all 20 mushrooms

What it is and how it is named

Oyster mushroom is the common name for Pleurotus ostreatus (family Pleurotaceae). GBIF lists it as an accepted species name. [3] A review describes Pleurotus mushrooms as widely cultivated around the world and rich in protein, fiber, amino acids, water-soluble vitamins and minerals. [4] For actual nutrient numbers, see mushroom nutrition. "Oyster mushroom" is also used loosely for related Pleurotus species, including king oyster. A result for one species does not transfer to the other.

Traditional use

Proper evidence not found: we did not read a source that describes traditional medicinal use of oyster mushroom, so we do not describe one. We searched PubMed and the reviews listed below.

What research shows

Human research is small and mostly short. All rows below are about the food itself unless stated.
QuestionWhat the source foundStrength of evidencePopulation, form and amount studied
Blood sugar and gut hormones after a mealGlucose, insulin and triglycerides did not differ; one fatty-acid measure was 14% lower and GLP-1 17% higher. [5]Promising but limited (single-meal biomarker changes, not clinical outcomes)22 adults with impaired glucose tolerance; meal with 20 g of oven-dried oyster mushroom powder
Thinking and mood, single sittingCognitive findings were mixed with no consistent pattern; a brain-growth-factor marker was lower after oyster mushroom. [6]Mixed33 healthy older adults; noodle soup with 0.5, 1 or 2 servings
Thinking and mood, 12 weeksThe oyster mushroom group scored better on delayed word recall and recognition and reported less negative mood than placebo. [7]Promising but limited (one trial)80 healthy adults aged 60 to 80; four portions a week
Heart and metabolic risk factorsIn an 8-week diet trial that used white button and oyster mushrooms together, fasting glucose improved and other risk factors did not change. [8]Mixed; cannot be assigned to oyster alone60 adults; 84 g a day of the two mushrooms combined
Overall picture for mushrooms and heart healthA systematic review found limited experimental evidence for triglycerides and hs-CRP, and rated most articles "poor" for quality. [9]Insufficient evidenceAll edible mushrooms combined

Two of the trials above compare against a calorie-matched or placebo food, which is the right design, but all are small. The cognition findings are from a single research group and have not, in what we read, been repeated by another. We did not read funding statements for these trials, so we do not report them. No trial we read tested cooked oyster mushroom as a treatment for any disease, and none supports using it to treat one.

Forms and why the form matters

Fresh or cooked oyster mushroom is a food. Powders and extracts are different products. The glucose trial used a dried powder stirred into a meal, and its result should not be applied to a fresh mushroom in a stir-fry or to an extract capsule. Supplement forms are covered in mushroom supplement forms; how a food portion compares is on food portions vs supplement amounts.

Official statements

Proper evidence not found: no regulator statement on oyster mushroom as a health product appeared in the sources we read.

Lab data and chemistry

This section is for readers who want the laboratory side. It describes what has been measured in oyster mushroom, not what it does in the body. For what people trials found, see the research table above.

What the laboratory literature reports in this mushroom

Wikidata, through the LOTUS natural-products project, lists 40 compounds as "found in" Pleurotus ostreatus. [10] A presence entry means "reported in at least one study of this species", not "present in every product". The copy of the data we hold does not name the paper behind each statement, so the table gives the Wikidata entry. The identity codes are Wikidata (Q) and ChEBI numbers taken from that copy. Ergothioneine and pleuran are not in that list of 40, but papers we read measured ergothioneine (table B) and tested a beta-glucan called pleuran.
Compound or groupClassWhere in the mushroom / formIdentitySource
LovastatinStatin-type compoundFruiting body, trace and very variable (see table B)Q417740; ChEBI 40303[10] [11] [12] [13]
ErgosterolSterol (the fungal sterol that makes vitamin D2 under UV light)Fruiting bodyQ143263; ChEBI 16933[10]
Ergosta-4,6,8,22-tetraen-3-oneSterol derivativeFruiting bodyQ77502015; ChEBI 218638[10]
LaminarinBeta-glucan type polysaccharideListed for the species; no ChEBI entryQ104251658[10]
D-Mannitol and D-sorbitolSugar alcoholsFruiting bodyQ407646 (ChEBI 16899); Q245280 (ChEBI 17924)[10]
Oct-1-en-3-ol, 3-octanol, 3-octanone, 2-octanone, 1-octanolVolatile aroma compoundsFresh mushroom aromaQ161667 (ChEBI 34118); Q27154917; Q18349104; Q18611679; Q161666[10]
Linoleic, oleic, palmitic and stearic acidFatty acidsFruiting bodyQ407426 (ChEBI 17351); Q207688 (16196); Q209727 (15756); Q209685 (28842)[10]
L-Glutamic acid, L-ornithine, (S)-pyroglutamic acid, D-alanineAmino acids and relativesFruiting bodyQ26995161 (ChEBI 16015); Q410198 (15729); Q60998677 (18183); Q27076975 (15570)[10]
Succinic acid and malic acidOrganic acidsFruiting bodyQ213050 (ChEBI 15741); Q190143 (6650)[10]
Sucrose, glucose, fructose, mannose, lactose, galacturonic acidSugars and sugar acidFruiting bodyQ4027534 (ChEBI 17992); Q21036645 (42758); Q122043 (48095); Q335208 (4208); Q56229948 (17716); Q422729 (47962)[10]
Benzaldehyde and benzoic acidAromatic compoundsReported for the speciesQ372524 (ChEBI 17169); Q191700 (30746)[10]
Oxalamido amino-acid esters and "POH" compoundsSmall peptide-like and unnamed compoundsReported for the species; little else knownQ105351201, Q105005120, Q77506746, Q77376678[10]
Pleuran (beta-glucan from this species)Beta-glucanPurified extract used in children's trials, not whole mushroomnot in the Wikidata list[14] [15] [16]
ErgothioneineDietary antioxidant amino acidFruiting bodynot in the Wikidata list; ChEBI id not checked[11] [13]

We checked these entries against the saved Wikidata file, not each paper behind them. The ChEBI numbers come from that file and were not opened on the ChEBI site.

Measured values

USDA FoodData Central, per 100 g raw edible portion. Two oyster records exist, and they disagree on some nutrients. Foundation Foods (FDC 1999627, 2021) is the newer one; SR Legacy (FDC 168580, 2018) is the older dataset. [17] [18]
MeasureValueBasisSampleSource
Energy33.3 kcal (Foundation); 139 kJ (SR Legacy)fresh, rawoyster, FDC 1999627; FDC 168580[17] [18]
Protein2.90 g; 3.31 gfresh, rawFDC 1999627; 168580[17] [18]
Total fat0.19 gfresh, rawFDC 1999627[17]
Carbohydrate, by difference6.94 gfresh, rawFDC 1999627[17]
Dietary fibre2.85 g; 2.3 gfresh, rawFDC 1999627; 168580[17] [18]
Beta-glucan1.92 gfresh, rawFDC 1999627[17]
Ergothioneine14.0 mgfresh, rawFDC 1999627[17]
Glutathione17.5 mgfresh, rawFDC 1999627[17]
Ergosterol58.49 mgfresh, rawFDC 1999627[17]
Vitamin D20.04 microgram (Foundation); 0.7 microgram (SR Legacy)fresh, raw; the records do not say whether the mushrooms saw UV lightFDC 1999627; 168580[17] [18]
Riboflavin (B2)0.244 mg; 0.349 mgfresh, rawFDC 1999627; 168580[17] [18]
Niacin (B3)5.75 mg; 4.96 mgfresh, rawFDC 1999627; 168580[17] [18]
Pantothenic acid (B5)1.294 mgfresh, rawFDC 168580 (not in the Foundation record)[18]
Folate63.1 microgram; 38 microgramfresh, rawFDC 1999627; 168580[17] [18]
Potassium282 mg; 420 mgfresh, rawFDC 1999627; 168580[17] [18]
Copper0.106 mg; 0.244 mgfresh, rawFDC 1999627; 168580[17] [18]
Selenium1.38 microgram; 2.6 microgramfresh, rawFDC 1999627; 168580[17] [18]

USDA lists vitamin D separately for UV-exposed mushrooms of other kinds (such as button and portabella). It has no UV-exposed oyster record in our copy, so we cannot show an exposed versus unexposed pair here. The 17-fold gap between the two oyster records is in the data as published; we did not find a source explaining it.

Other measured values from papers.

MeasureValueBasisSampleSource
Ergothioneine607.3 mg per kg (LC-MS)dry weight, fruiting bodyP. ostreatus on wheat straw, 3 replicates[13]
Ergothioneine1829.4 and 1458.4 mg per kgfruiting body, dry basis as described in the abstractKorean and Taiwanese P. ostreatus samples[11]
Lovastatin1.11 mg per kg (LC-MS)dry weight, fruiting bodyP. ostreatus on wheat straw, 3 replicates[13]
Lovastatin606.5 mg per kgfreeze-dried fruiting bodyJapanese-sourced P. ostreatus[11]
Lovastatinnot detectedraw fruiting bodyP. ostreatus, raw[12]
Beta-glucan23.9 percent of dry matter (dry matter 8 percent)raw fruiting bodyP. ostreatus, raw[12]
Beta-glucan8.1 g in 20 g of oven-dried powder (about 40 percent)oven-dried powderpowder used in the glucose trial[5]
Total polyphenols487 mg gallic acid equivalents per 100 g dry matterraw fruiting bodyP. ostreatus, raw[12]

Two of the beta-glucan figures can be compared. Multiplying 23.9 percent by 8 percent dry matter gives about 1.9 g per 100 g fresh (our own arithmetic), which matches USDA's 1.92 g. The trial powder's 8.1 g in 20 g is far higher, so a different assay or a different product was probably involved; the trial abstract does not say. A 2006 survey of cultivated mushrooms found 0.4 to 2.0 mg of ergothioneine per g dry weight overall; oyster, shiitake, king oyster and maitake did not differ from one another and all had more than white button. [19]

What the numbers do and do not mean

  • Methods change the answer. For lovastatin in oyster, the papers we read report "not detected", about 1 mg per kg and about 600 mg per kg. The 2021 paper also found that a cheaper UV light-absorption method gave results hundreds of times higher than LC-MS, because other compounds in the mushroom interfere. [13] Treat all lovastatin figures as unsettled. We found no source showing that eating oyster mushroom lowers cholesterol or acts like a statin medicine.
  • A compound in the mushroom is not a health effect. Ergothioneine is a food antioxidant, and oyster is among the richer sources in the papers we read. The older-adult trials above used the whole mushroom, and the mechanisms were not shown. [6] [7]
  • Food portion versus supplement. USDA's 14 mg ergothioneine per 100 g is for eating the mushroom. We found no oyster mushroom supplement with a measured value, so we give none.
  • "Beta-glucan" depends on the test. A trial powder at about 40 percent, a raw mushroom at 24 percent of dry matter and USDA's 1.92 g per 100 g fresh are different bases, not a contradiction. Pleuran in the children's trials is a purified extract, so those results do not carry over to eating the mushroom. [14] [15] [16] Mycelium-on-grain products (see fruiting body vs mycelium) can also count grain starch in a "polysaccharide" figure; we found no oyster measurement of that.
  • Ranges vary by strain, growing material, harvest, drying and extraction. One study found that drying cut lovastatin by about 70 to 84 percent, so a dried product is not the same as a fresh mushroom. [20]

Pleuran and other chemistry-linked trials

Pleuran is a beta-glucan purified from P. ostreatus. One randomised, double-blind trial of 175 children with frequent respiratory infections compared a pleuran and vitamin C syrup with vitamin C alone; 36 percent of the pleuran group had no infections over the treatment period versus 21 percent on placebo. [14] A later trial of 249 children (217 completed) found 15.2 percent fewer respiratory infections over 3 months with a chewable pleuran, vitamin D and zinc product than with vitamin D and zinc alone. [15] A trial in 230 children with partly controlled asthma found asthma control better in children under 12, and fewer infections in those 12 and over. [16] These are promising but limited: most come from one research group, we read only the abstracts, and we did not read funding statements. The products were purified extracts combined with vitamins or minerals. They say nothing about cooked oyster mushroom or powders.

Safety notes from the laboratory literature

  • Oyster mushroom, like other mushrooms, takes up metals from its growing material. A 2024 laboratory study that added cadmium or mercury to the growing medium found that the mushroom concentrated them. [21] This is not a measurement of shop products, but it is why growing material and testing matter; see heavy metals and contamination.
  • A 2024 study of oyster mycelium found no regulated mycotoxins and reported four peptide toxins that were lower in mycelium than in fruiting bodies, which are already eaten. [22] Cooking is still advised; see cooking edible mushrooms safely.

Frequently asked questions

Is oyster mushroom good for you?

It is a nutritious food according to a review of Pleurotus nutrition, which describes protein, fiber and vitamins. [4] Whether eating it changes health outcomes is not established: small trials show some short-term changes and a systematic review of mushroom eating rated the evidence limited. [9]

Does oyster mushroom improve memory?

One 12-week trial in 80 healthy older adults found better delayed word recall than placebo, but a single-meal trial found mixed results. [7] [6] That is promising but limited, and it does not show benefit for people with memory loss or dementia.

Can oyster mushroom lower blood sugar?

A single-meal trial in adults with impaired glucose tolerance did not find lower glucose after a meal with oyster powder. [5] Anyone managing diabetes should follow their care team's plan.

Can you be allergic to oyster mushroom?

Yes. Case reports describe asthma and anaphylaxis from the spores in people who grow or sell it. [1] [2]

Is a wild mushroom that looks like an oyster mushroom safe?

We give no identification guidance. Wild mushroom poisoning can be serious; call Poison Help at 1-800-222-1222 and see mushroom poisoning and urgent help.

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety first: spore allergy is the documented risk
Oyster mushroom is an ordinary food for most people. The documented health problem is allergy to its spores, mostly reported in people who grow, pack or sell it. One report describes a woman on an oyster mushroom farm who developed work-related asthma and anaphylaxis, and notes that spores are "highly potent allergens". [1] Another describes a market vendor whose asthma was traced to Pleurotus ostreatus spores and who improved after stopping handling mushrooms. [2] These are single case reports: they show the reaction can happen, not how often. If breathing trouble, hives or swelling follow handling or eating mushrooms, get medical care; call 911 for severe symptoms. More on mushroom allergy and food intolerance.

Never eat a wild mushroom because it "looks like" an oyster mushroom. Poison Help is 1-800-222-1222 (US), and the page on plant and mushroom poisoning explains what to do. This page covers shop-bought, cultivated oyster mushrooms as food only.

Safety for specific groups
  • Medicines: we did not read a source that documents an interaction between eating oyster mushroom and a medicine. That is not proof of safety. Ask a pharmacist, and see how interactions work. People taking diabetes medicines should not assume a mushroom meal changes what their prescriber has advised.
  • Pregnancy, breastfeeding, children, older adults, liver and kidney disease, surgery: not described in the sources we read for oyster mushroom as a food. The older-adult trials above reported on healthy people aged 60 to 80 only. General guidance is on pregnancy and breastfeeding.
  • Cooking: this library explains why cooking matters for edible mushrooms in cooking edible mushrooms safely and storage in storing mushrooms.
  • Contamination and mislabeling: applies mostly to dried and powdered products; see quality testing and certifications.
References
  1. Branicka O, et al. A case of anaphylactic reaction following oyster mushroom (Pleurotus ostreatus) inhalation. International Journal of Occupational Medicine and Environmental Health, 2021. Read 2026-10-22.
  2. Baldassarre A, et al. Occupational asthma in a fruit and vegetables vendor. Medicina del Lavoro, 2016. Read 2026-10-22.
  3. Global Biodiversity Information Facility (GBIF), species match for Pleurotus ostreatus, usage key 2526530. GBIF species page. Read 2026-10-22 through the GBIF species-match service.
  4. Raman J, et al. Cultivation and Nutritional Value of Prominent Pleurotus spp.: An Overview. Mycobiology, 2020. Read 2026-10-22.
  5. Dicks L, et al. Fortifying a meal with oyster mushroom powder ... in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial. European Journal of Nutrition, 2022. Read 2026-10-22.
  6. Cha S, et al. A randomised controlled study ... acute oyster mushroom intervention in healthy older adults. Food & Function, 2026. Read 2026-10-22.
  7. Cha S, et al. A randomised controlled study ... chronic oyster mushroom intervention in healthy older adults. Food & Function, 2026. Read 2026-10-22.
  8. Uffelman CN, et al. Consuming Mushrooms When Adopting a Healthy Mediterranean-Style Dietary Pattern Does Not Influence Short-Term Changes of Most Cardiometabolic Disease Risk Factors. Journal of Nutrition, 2024. Read 2026-10-22.
  9. Uffelman CN, et al. An Assessment of Mushroom Consumption on Cardiometabolic Disease Risk Factors and Morbidities in Humans: A Systematic Review. Nutrients, 2023. Read 2026-10-22.
  10. Wikidata (CC0), compound-in-taxon statements for Pleurotus ostreatus (Q186451), from the LOTUS initiative; read through the project's saved copy retrieved 2026-10-23 (docs/research/mushroom-lab-sources/lotus-oyster.json). Wikidata Q186451.
  11. Chen SY, et al. Contents of lovastatin, gamma-aminobutyric acid and ergothioneine in mushroom fruiting bodies and mycelia. LWT - Food Science and Technology, 2012. Abstract read through Europe PMC 2026-10-24.
  12. Lam YS, Okello EJ. Determination of Lovastatin, beta-glucan, Total Polyphenols, and Antioxidant Activity in Raw and Processed Oyster Culinary-Medicinal Mushroom. International Journal of Medicinal Mushrooms, 2015. Abstract read through Europe PMC 2026-10-24.
  13. Tsiantas K, et al. On the Identification and Quantification of Ergothioneine and Lovastatin in Various Mushroom Species. Molecules, 2021. Open access; Table 3 read through Europe PMC 2026-10-24.
  14. Jesenak M, et al. Immunomodulatory effect of pleuran (beta-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections. International Immunopharmacology, 2013. Abstract read through Europe PMC 2026-10-24.
  15. Jesenak M, et al. Novel Chewable Pleuran-Based Supplement Decreases Respiratory Tract Infections in Children: A Randomised Controlled Trial. Advances in Therapy, 2025. Abstract read through Europe PMC 2026-10-24.
  16. Jesenak M, et al. Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma. Scientific Reports, 2025. Abstract read through Europe PMC 2026-10-24.
  17. U.S. Department of Agriculture. FoodData Central, Foundation Foods, FDC ID 1999627, Mushroom, oyster. Public domain; read from the project's saved copy of the 2025-12-18 download.
  18. U.S. Department of Agriculture. FoodData Central, SR Legacy, FDC ID 168580, Mushrooms, oyster, raw. Public domain; read from the project's saved copy of the SR Legacy download.
  19. Dubost NJ, et al. Identification and quantification of ergothioneine in cultivated mushrooms by liquid chromatography-mass spectroscopy. International Journal of Medicinal Mushrooms, 2006. Abstract read 2026-10-24.
  20. Demiray E, Caliskan Koc G. Effect of vacuum drying temperature and pressure on the drying and desorption characteristics, and lovastatin content of the oyster mushroom (Pleurotus ostreatus) slices. Journal of Food Processing and Preservation, 2021. Abstract read through Europe PMC 2026-10-24.
  21. Liu Q, et al. Enrichment characteristics of Cd and Hg and regulation of heavy metal transporter signaling in Pleurotus ostreatus. Science of the Total Environment, 2024. Abstract read through Europe PMC 2026-10-24.
  22. van Dam L, et al. GastronOmics: Edibility and safety of mycelium of the oyster mushroom Pleurotus ostreatus. Current Research in Food Science, 2024. Abstract read through Europe PMC 2026-10-24.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.