Olive Leaf (Olea europaea): Uses, Evidence and Safety
Olive leaf (Olea europaea): what EU regulators and trials say about blood pressure, blood sugar and water retention, who should ask first, and what is not known.
Content last updated . This page has not been medically reviewed.

Safety first. Supplements can cause side effects and interact with medicines. Read mushroom safety and interactions before you use any mushroom product.
What is Olive leaf good for?
What the body uses it for, and how strong the evidence is. A normal job in the body is not proof that extra supplements add benefit; each card says which.
Blood pressure (small to moderate drops in trials)
Preliminary or mixedSeveral trials of olive leaf extract in adults with raised blood pressure found lower readings. Pooled reviews call the evidence limited because trials were small and used different extracts.
Supplements: Results come from specific extracts in adults with raised blood pressure; they cannot be assumed for leaf tea or other products, and it is not a substitute for prescribed medicine.
Blood fats (mainly triglycerides)
Preliminary or mixedA pooled review found lower triglycerides after olive leaf extract, with low-quality evidence. Other fat measures changed mainly in people with high blood pressure.
Supplements: Small, low-quality evidence; not shown to prevent heart disease.
Blood sugar control in type 2 diabetes
Preliminary or mixedOne 14-week trial found lower HbA1c with an extract, but a later 24-week pilot trial was inconclusive. A trial of a combination product in prediabetes found no effect.
Supplements: Mixed evidence; anyone on diabetes medicine should ask the prescriber first.
Mild water retention (traditional use)
Not enough evidenceThe EU herbal committee accepted that olive leaf can be used to promote water elimination through the kidneys in mild water retention in adults, based on long-standing use only, after a doctor has ruled out serious causes.
Supplements: Tradition, not proof; no trial evidence is cited by the regulator.
Inflammation markers
Preliminary or mixedOne large trial reported lower CRP with the extract, but a pooled review found no meaningful change in inflammatory markers and rated the evidence low to very low.
Supplements: Mixed, low-quality evidence; not shown to help any inflammatory condition.
Antioxidant (polyphenol) activity
Lab or animal research onlyOlive leaf contains plant polyphenols such as oleuropein, which are studied in the laboratory. No source read here shows this translates to a health benefit in people.
Supplements: No evidence from the sources read that this gives a benefit in people.
Connected topics
Open a group to see how each topic connects and how strong the evidence is.
Health goals (3)
- Blood Pressure SupportPreliminary or mixed
Some trials of olive leaf extract found lower blood pressure, but pooled reviews call the evidence limited. It does not replace prescribed medicine.
- Blood Sugar BalancePreliminary or mixed
One trial found lower HbA1c in type 2 diabetes, a later pilot was inconclusive and a combination product showed no effect in prediabetes.
- Cholesterol BalancePreliminary or mixed
A pooled review found lower triglycerides and, in people with high blood pressure, lower cholesterol, but rated the evidence low quality.
Body systems (3)
- Cardiovascular SystemPreliminary or mixed
Some trials of olive leaf extract found lower blood pressure, but pooled reviews call the evidence limited. It does not replace prescribed medicine.
- Heart & CirculationPreliminary or mixed
Some trials of olive leaf extract found lower blood pressure, but pooled reviews call the evidence limited. It does not replace prescribed medicine.
- Blood Sugar SupportPreliminary or mixed
Results on blood sugar are mixed: one positive trial, one inconclusive pilot.
Functional actions (2)
- Cardiovascular SupportPreliminary or mixed
Some trials of olive leaf extract found lower blood pressure, but pooled reviews call the evidence limited. It does not replace prescribed medicine.
- Blood Sugar RegulationPreliminary or mixed
Mixed trial results on HbA1c in type 2 diabetes; lab data suggest reduced starch absorption.
Biomarkers (2)
- HbA1cPreliminary or mixed
One 14-week trial found lower HbA1c with an extract; a 24-week pilot found no clear difference.
- TriglyceridesPreliminary or mixed
A pooled review of 12 trials found lower triglycerides, with low-quality evidence.
Conditions & symptoms (2)
- Essential HypertensionPreliminary or mixed
Trials in adults with raised blood pressure found lower readings with olive leaf extract; evidence is limited and varies by product.
- Diabetes Mellitus, Non-Insulin-DependentPreliminary or mixed
One trial found lower HbA1c, a later pilot was inconclusive. Not a replacement for diabetes medicine.
Documented risks and interactions (5)
- Contraindicated where fluid intake must be limited. The EU committee says olive leaf medicines must not be used by people told to limit fluids, such as with severe heart or kidney disease.
- Not recommended for children and under 18. The EU committee says olive leaf medicines should only be used in adults.
- Pregnancy and breastfeeding: safety not established. Safety in pregnancy and breastfeeding has not been established, so use is not recommended without advice from a clinician.
- Possible added effect with blood pressure or diabetes medicines. Because trials show blood pressure and blood sugar effects, a prescriber should know about olive leaf use. No specific interaction has been documented in the sources read.
- Tolerability in trials. The 621-person trial reported no significant adverse events and the ESOLED pilot reported none serious. The EU regulator had received no reports of side effects at the time of assessment.
Safety first. Olive leaf products have been studied for lowering blood pressure, so anyone who takes blood pressure or diabetes medicine should tell the prescriber or pharmacist before adding one. The EU herbal committee says olive leaf medicines must not be used by people who are told to limit fluids, such as those with severe heart or kidney disease. [1] It also says safety in pregnancy and breastfeeding has not been established and that use under 18 has not been established. [2] See How Interactions Work.
Overview
Olive leaf is the leaf of the olive tree, not the fruit or the oil. [1] It is sold as dried leaf for tea, as capsules and as concentrated extracts. This page covers the leaf. For olive oil as a food, see Olive Oil. The trials below mostly tested extracts, and a result for one extract does not carry over to a cup of leaf tea.Scientific name and plant part
- Accepted name: Olea europaea L., family Oleaceae, according to the GBIF plant database. [3]
- Part used: the leaf. The EU committee's conclusions cover fresh or dried leaves and preparations made by drying and powdering them. [1]
Traditional use (not proof)
A 2012 trial paper notes that olive leaves have been widely used in traditional remedies in European and Mediterranean countries, as extracts, herbal teas and powder. [4] The EU herbal committee (HMPC) accepted, on the basis of long-standing use, that olive leaf can be used to promote water elimination through the kidneys in mild water retention, in adults, after a doctor has ruled out serious conditions. [1] It said this rests on long-standing use because clinical evidence was insufficient. [1] Tradition is respected as history here and is not treated as proof.What research shows (research, not tradition)
| Use | What the source found | Evidence label | Population and form studied |
|---|---|---|---|
| Blood pressure in stage-1 hypertension | In an 8-week trial, an olive leaf extract lowered blood pressure about as much as the medicine captopril (systolic -11.5 vs -13.7 mmHg). [5] | Promising but limited | Adults with stage-1 hypertension; one extract |
| Blood pressure in people already treated for hypertension | A 12-week trial of 621 people found 24-hour systolic pressure fell 6.4 mmHg with the extract and 1.5 mmHg with placebo. [6] | Promising but limited | Treated hypertension; one extract |
| Blood pressure, pooled trials | A 2022 review of 12 studies found a pooled systolic drop of about 3.9 mmHg. [7] A 2021 review found the evidence did not support a robust conclusion because trials were small. [8] | Mixed | Adults; many extracts and amounts |
| Pre-hypertension | A crossover trial in 60 men found 24-hour systolic pressure about 3.3 mmHg lower than control. [9] Half the funding came from the extract's manufacturer. [9] | Promising but limited | Men with pre-hypertension; 6 weeks |
| Blood fats | The 2022 review found lower triglycerides (about 9.5 mg/dl), with limited quality of evidence. [7] | Promising but limited | Adults; mixed extracts |
| Blood sugar | A 14-week trial in 79 adults with type 2 diabetes found lower HbA1c with an extract. [4] A 24-week pilot of 31 adults was inconclusive. [10] A 6-month trial of a combination product found no change in prediabetes. [11] | Mixed | Type 2 diabetes or prediabetes; different products |
| Mild water retention | Accepted by the EU regulator on long-standing use only. [1] | Traditional use only | Adults; leaf preparations |
Beyond these uses, Proper evidence not found in the sources we read. We searched PubMed for olive leaf extract with blood pressure, blood sugar and adverse effects, and read the EU regulator's summary and monograph.
Forms and why the form matters
Trials used extracts with different contents. One crossover trial gave 136 mg oleuropein a day. [9] Another gave 51.1 mg oleuropein a day. [12] Because of this, the results of one product cannot be assumed for another. The EU committee's conclusions cover leaf teas and solid forms and exclude combination products. [1] See Standardized Herbal Extracts Explained.Safety and who should ask first
- Medicines: the EU monograph (2017) lists no interactions as reported. [2] Our reading, not a documented harm: the trials above show blood pressure effects close to a prescription medicine, so a prescriber should know about the combination. See Herbs and Diabetes, Blood Pressure and Heart Medicines.
- Heart and kidney conditions: the monograph says people with cardiac disease or renal impairment should seek medical advice first. [2]
- Pregnancy and breastfeeding: not established; the monograph does not recommend use. [2] See Pregnancy and Breastfeeding.
- Children: not established under 18. [2]
- Side effects: the 621-person trial reported no significant adverse events. [6] The EU monograph lists none known. [2]
- Liver and kidney blood tests: a 2022 review found no meaningful change, but rated this evidence low to very low quality. [7]
- Allergy, bleeding and surgery: the sources we read did not give olive-leaf-specific points. Tell the surgical team about every herb you use. See Supplements Before Surgery.
- Quality: contents of products can differ from labels. See Quality Testing and Certifications.
Official statements
- EU herbal committee (HMPC), monograph dated 31 January 2017: traditional use for mild water retention in adults; contraindicated where fluid intake must be limited. [2][1]
Frequently asked questions
Does olive leaf lower blood pressure?
Some trials say yes, by a few to about 11 mmHg, but pooled reviews call the evidence limited because trials were small and varied. [7][8] It is not a substitute for prescribed medicine. Ask the prescriber or pharmacist.
Is olive leaf the same as olive oil?
No. Olive leaf comes from the leaf of Olea europaea; the oil comes from the fruit. [1] See Olive Oil.
Can olive leaf help with diabetes?
Results are mixed. One trial found lower HbA1c, and a later pilot was inconclusive. [4][10] Talk to the care team before using it with diabetes medicine.
Is olive leaf safe in pregnancy or for children?
Safety has not been established for pregnancy, breastfeeding or under 18. [2] Ask a clinician. See Children and Teens.
Who should not use olive leaf medicines?
The EU committee says people who must limit fluid intake, such as with severe heart or kidney disease, should not. [1]
Related: Hawthorn, Hibiscus, Garlic, Herbs for Blood Pressure and Cholesterol.
References
- European Medicines Agency, HMPC. Oleae folium (olive leaf): herbal medicinal product, summary of conclusions. ema.europa.eu. Read 2026-10-23.
- European Medicines Agency, HMPC. European Union herbal monograph on Olea europaea L., folium (EMA/HMPC/359238/2016, final, 31 January 2017). ema.europa.eu. Read 2026-10-23.
- GBIF Secretariat. GBIF Backbone Taxonomy: Olea europaea L. api.gbif.org species match. Read 2026-10-23.
- Wainstein J, et al. Olive leaf extract as a hypoglycemic agent in both human diabetic subjects and in rats. J Med Food. 2012. PubMed 22512698. Read 2026-10-23.
- Susalit E, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine. 2011. PubMed 21036583. Read 2026-10-23.
- Lamti F, et al. Efficacy of olive leaf extracts in controlling blood pressure in hypertensive patients: a double-blind randomized clinical trial. J Hypertens. 2025. PubMed 40990594. Read 2026-10-23.
- Razmpoosh E, et al. The effects of olive leaf extract on cardiovascular risk factors in the general adult population: a systematic review and meta-analysis of randomized controlled trials. Diabetol Metab Syndr. 2022. PubMed 36271405. Read 2026-10-23.
- Ismail MA, et al. Olive leaf extract effect on cardiometabolic profile among adults with prehypertension and hypertension: a systematic review and meta-analysis. PeerJ. 2021. PubMed 33868820. Read 2026-10-23.
- Lockyer S, et al. Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial. Eur J Nutr. 2017. PubMed 26951205. Read 2026-10-23.
- Leach MJ, Breakspear I. Efficacy and safety of olive leaf extract (Olea europaea L.) for glycaemic control in adults with type 2 diabetes mellitus (ESOLED): a pilot randomised controlled trial. Complement Ther Clin Pract. 2025. PubMed 39818111. Read 2026-10-23.
- Florentin M, et al. No effect of fenugreek, bergamot and olive leaf extract on glucose homeostasis in patients with prediabetes: a randomized double-blind placebo-controlled study. Arch Med Sci Atheroscler Dis. 2019. PubMed 31448348. Read 2026-10-23.
- de Bock M, et al. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PLoS One. 2013. PubMed 23516412. Read 2026-10-23.