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Every herb, ingredient, formula, gene target, and disease — connected through real research. Search, pick a subject, and navigate the graph in any direction.

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Evidence

23,295

trials · metas · refs

Plus 6,743 TCM formulas connecting herbs together

Subject Type: 🌿 Herbs ⚗️ Ingredients 📜 Formulas 🧬 Targets 🏥 Diseases

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⚗️ Ingredient

O-thymol

Open on HERB 2.0 ↗

Clinical Trials

Meta-Analyses

PubMed References

Top Conditions Studied with O-thymol

COVID-19|COVID-19 Pneumonia|COVID-19 Respiratory Infection|C 1

📋 Sample Trials

NCT05445089

Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound Against SARS-CoV-2 in COVID-19 Patients

Completed · Phase 2|Phase 3

📊 Sample Meta-Analyses

CRD42020176736

Antitumor activity of carvacrol and thymol - a systematic review [provisional title]

📚 Sample References

PMID 30486272

Carvacrol Attenuates Hippocampal Neuronal Death after Global Cerebral Ischemia via Inhibition of Transient Receptor Potential Melastatin 7

Cells · 2018

PMID 23791894

Eugenol and carvacrol induce temporally desensitizing patterns of oral irritation and enhance innocuous warmth and noxious heat sensation on the tongue

Pain · 2013

PMID 33989663

Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephrotoxicity by molecular targeting regulation

Life Sci · 2021

⚗️ All Ingredient data fields for O-thymol

⚗️ Identity

Name

O-thymol

Aliases / Synonyms

CARVACROL; 5-Isopropyl-2-methylphenol; 499-75-2; Isopropyl-o-cresol; Antioxine; 2-p-Cymenol; 5-Isopropyl-o-cresol; Isothymol; Karvakrol

🧪 Chemistry

Molecular Weight

150.2210

LogP

2.8240

Drug-likeness

0.652

Oral Bioavailability

43.2810

H-Bond Acceptors

H-Bond Donors

Rotatable Bonds

🔬 Structures

Canonical SMILES

CC1=C(C=C(C=C1)C(C)C)O

Isomeric SMILES

CC1=C(C=C(C=C1)C(C)C)O

InChIKey

RECUKUPTGUEGMW-UHFFFAOYSA-N

InChI

InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

🔗 External References

HERB DB

HBIN038398 ↗

PubChem CID

10364 ↗

CAS Number

499-75-2; 449-75-2 ↗

NPASS

NPC312132

HIT

C1218

TCMID

24138; 3231; 24653; 40440

TCMSP

MOL000259

TCM-ID

2003; 14438; 1817; 8571; 8532

🔍 Raw view — every non-empty column on this row (33 fields)

name

O-thymol

common names

CARVACROL; 5-Isopropyl-2-methylphenol; 499-75-2; Isopropyl-o-cresol; Antioxine; 2-p-Cymenol; 5-Isopropyl-o-cresol; Isothymol; Karvakrol

herb ingredient id

HBIN038398

canonical smiles

CC1=C(C=C(C=C1)C(C)C)O

isomeric smiles

CC1=C(C=C(C=C1)C(C)C)O

inchi

InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

inchikey

RECUKUPTGUEGMW-UHFFFAOYSA-N

mol wt

150.2210

num h acceptors

num h donors

mol logp

2.8240

num rotatable bonds

drug likeness

0.652

ob score

43.2810

cas id

499-75-2; 449-75-2

tcmid ingredient id

24138; 3231; 24653; 40440

tcmsp ingredient id

MOL000259

tcm id ingredient id

2003; 14438; 1817; 8571; 8532

pubchem cid

10364

npass id

NPC312132

hit id

C1218

📋 Clinical Trials

1 · subject of clinical study

NCT05445089 Study to Verify the Effectiveness and Safety of Isothymol or Carvacrol Compound

→ COVID-19|COVID-19 Pneumonia|COVID-19 Respiratory I

📊 Meta-Analyses

1 · systematic review

CRD42020176736 Antitumor activity of carvacrol and thymol - a systematic review [provisional ti

📚 PubMed References

6 · cited research

PMID 30486272 Carvacrol Attenuates Hippocampal Neuronal Death after Global Cerebral Ischemia v

Cells

PMID 23791894 Eugenol and carvacrol induce temporally desensitizing patterns of oral irritatio

Pain

PMID 33989663 Modulatory effects of carvacrol against cadmium-induced hepatotoxicity and nephr

Life Sci

PMID 34089284 Systemic inflammation and oxidative stress induced by inhaled paraquat in rat im

Biofactors

PMID 35150742 Molecular determinants for the chemical activation of the warmth-sensitive TRPV3

J Biol Chem

PMID 35276864 Carvacrol Suppresses Inflammatory Biomarkers Production by Lipoteichoic Acid- an

Nutrients

How relationships are computed

Clinical Trials / Meta-Analyses / References: direct foreign-key link via subject_entity_id (Phase 2d wireup)
Formula ↔ Herbs: text bridge via formulas.herbs_in_pinyin matching herbs.pinyin_name
Herb ↔ Ingredient: ACTIVE — direct link via herb_ingredients
Ingredient ↔ Target: ACTIVE — direct link via ingredient_targets
Target ↔ Disease: ACTIVE — direct link via target_health_topics
Herb → Target → Disease (full chemical spine): ACTIVE — joins all three link tables