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Understanding Vitamins: Types, Needs, Deficiency and Excess

A plain guide to vitamins: the 13 essential ones, fat- versus water-soluble, how needs are set, deficiency, excess, fortified foods, supplements and where to read next.

Content last updated . This page has not been medically reviewed.

Overview

Vitamins are nutrients the body needs in small amounts to work properly. The NHS (UK) says most people should get all the nutrients they need from a varied and balanced diet, although some people may need extra supplements. [1] MedlinePlus (US National Library of Medicine) describes vitamins as substances needed for normal cell function, growth and development. [2]

This page is information only. It is not medical advice, and a clinician or pharmacist who knows your health history is the right person to ask about a specific vitamin, a medicine or a symptom.

The 13 essential vitamins

MedlinePlus lists 13 essential vitamins: A, C, D, E, K, and the B vitamins thiamin (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), B6, biotin (B7), folate (B9) and B12. [2] It also names choline and carnitine as vitamin-like nutrients that are not on that list. [2] A role-by-role table is on What Is a Vitamin? The 13 Essential Vitamins.

Fat-soluble and water-soluble

Fat-soluble (A, D, E, K)Water-soluble (C and the B vitamins)
StorageStored in the liver, fatty tissue and muscles [2]Not stored; leftover amounts leave in urine. B12 is the exception and can be stored in the liver for many years [2]
AbsorptionAbsorbed more easily with dietary fat [2]See how the body absorbs vitamins
Why excess mattersMedlinePlus warns fat-soluble supplements can build up and may cause harm [2]Large amounts can still cause problems, for example vitamin B6 at 200 mg a day or more and nerve symptoms (NHS) [3]

"Water-soluble" does not mean harmless. The full comparison is on Fat-Soluble vs Water-Soluble Vitamins.

Where vitamins come from

Food is the main source. Vitamin D is also made in the skin with sunlight, though the NHS says people in the UK do not make enough from sunlight between October and early March. [2][4] Gut bacteria make some vitamin K, and bowel bacteria can make vitamin B6 and biotin. [5][3] Vitamin B12 occurs naturally only in foods of animal origin, so fortified foods or supplements matter for people who eat no animal foods. [2] See Vitamin B12 for Vegetarians and Vegans.

Needs differ by country

Each country sets its own reference amounts, so one number is never universal. For vitamin C in adults:
BodyGroupFigureSource and year
NHS (UK)Adults 19 to 6440 mg a dayNHS page, last reviewed 2020 [6]
US Dietary Reference Intakes (RDA)Men 19 and older / women 19 and older90 mg / 75 mg a dayMedlinePlus, reviewed January 2025 [7]
FDA label Daily ValueUS labels90 mgFDA Daily Value page [8]

An RDA is the average daily intake level enough to meet the needs of nearly all (97% to 98%) healthy people; an Adequate Intake (AI) is set when evidence is too limited for an RDA. [2] The Daily Value is the reference amount used to calculate %DV on US labels. [8] EFSA (EU) defines the Tolerable Upper Intake Level (UL) as the maximum level of total chronic daily intake from all dietary sources not expected to pose a risk. [9] Amounts used in studies are study amounts, not advice. See RDA, AI, DV and UL.

Deficiency versus low intake

MedlinePlus says a deficiency occurs when you do not get enough of a certain vitamin, and that it can cause health problems. [2] Examples include scurvy from lack of vitamin C [6] and anemia from too little B12. [3] Vitamin A deficiency is very rare in the United States, [10] and vitamin K deficiency is very rare, though it can follow long-term antibiotic treatment. [11] A tired feeling or a symptom on its own cannot confirm a shortage, and treating a suspected deficiency yourself is not advised: for example, folic acid above 1 mg a day can mask vitamin B12 deficiency, according to the NHS. [3] Blood tests have limits too: see Vitamin Deficiency Testing and Who Is at Risk of Vitamin Deficiency?.

Too much

Most harm from excess comes from supplements, not from food. Examples from the NHS: too many vitamin D supplements over a long time can cause too much calcium to build up; [4] the NHS says some research suggests an average of more than 1.5 mg of vitamin A a day over many years may affect bones, and many multivitamins and fish liver oils contain vitamin A; [12] high doses of nicotinic acid (a form of niacin) can cause flushing and, over a long time, liver damage; [3] and folic acid above 1 mg a day can mask vitamin B12 deficiency. [3] MedlinePlus adds that high-dose vitamin E supplements might raise the risk of bleeding in the brain. [13] See Vitamin Toxicity: Which Vitamins Have Upper Limits.

Urgent: if a child may have swallowed vitamins or supplements, call Poison Help at 1-800-222-1222 (US) or 911 if the person is unwell. Other countries: Poison Help by Country.

Fortified foods and supplements

Some foods have vitamins added. The NHS lists fat spreads and breakfast cereals fortified with vitamin D, [4] MedlinePlus lists fortified soymilk and cereals as B12 sources, [2] and notes that many US foods are now fortified with folic acid. [2] What is added differs by country: the NHS says UK cows' milk is generally not fortified with vitamin D "as it is in some other countries". [4] Fortified foods and supplements both count toward your total, so check labels. See Fortified and Enriched Foods.

MedlinePlus says supplements can be helpful during pregnancy and for special medical problems, and advises against taking more than 100% of the RDA without a provider's supervision. [2] Whether food is enough is covered on Food vs Supplement Sources and Are Vitamin Supplements Necessary?.

Explore the library

The full list is at the Vitamins hub.

Frequently asked questions

Do I need a vitamin supplement?

The NHS says most people should get what they need from a varied, balanced diet, though some people need extra supplements. [1] Whether you are one of them is a question for a clinician or pharmacist. See Do I Need a Supplement?.

What is the difference between fat-soluble and water-soluble vitamins?

Fat-soluble vitamins (A, D, E, K) are stored in the liver, fatty tissue and muscles; water-soluble ones (C and the B vitamins) mostly leave in urine, with B12 stored in the liver for many years. [2]

Can you take too much of a vitamin?

Yes. MedlinePlus says high doses of certain vitamins can be toxic. [2] The NHS gives examples for vitamins A, D and B6. [12][4][3]

Is choline a B vitamin?

No. MedlinePlus lists choline as a vitamin-like nutrient, not one of the 13 essential vitamins. [2] See Choline.

Are fortified foods the same as supplements?

Both add vitamins to your intake; fortified foods put them into everyday foods such as cereals or spreads. [4] Both count toward your total, so check labels before adding a supplement.

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety points for everyone
  • Medicines: vitamins can interact with medicines. For example, vitamin K affects how warfarin works. [11] See Medication Interactions.
  • Pregnancy and breastfeeding: the NHS advises avoiding liver and liver products in pregnancy because of their vitamin A content. [12] Ask your care team before any supplement: Pregnancy and Breastfeeding.
  • Children, older adults, kidney or liver conditions, and surgery: these groups can have different needs and risks. Talk to a clinician or pharmacist first; see Vitamins Before Surgery.
  • Quality: products vary. See Quality Testing and Certifications.
References
  1. NHS (UK). Vitamins and minerals: Overview. Page last reviewed 3 August 2020. Read 2026-10-22.
  2. MedlinePlus, U.S. National Library of Medicine. Vitamins (encyclopedia article, reviewed 1/21/2025). Read 2026-10-22.
  3. NHS (UK). Vitamins and minerals: B vitamins and folic acid. Page last reviewed 3 August 2020. Read 2026-10-22.
  4. NHS (UK). Vitamins and minerals: Vitamin D. Page last reviewed 3 August 2020. Read 2026-10-22.
  5. NIDDK, U.S. National Institutes of Health. Your Digestive System & How it Works. Last reviewed December 2017. Read 2026-10-22.
  6. NHS (UK). Vitamins and minerals: Vitamin C. Page last reviewed 3 August 2020. Read 2026-10-22.
  7. MedlinePlus, U.S. National Library of Medicine. Vitamin C (encyclopedia article, reviewed 1/21/2025). Read 2026-10-22.
  8. U.S. Food and Drug Administration. Daily Value on the Nutrition and Supplement Facts Labels. Read 2026-10-22.
  9. European Food Safety Authority. Overview on Tolerable Upper Intake Levels as derived by the Scientific Committee on Food (SCF) and the EFSA NDA Panel, version 11, August 2025. Read 2026-10-22.
  10. MedlinePlus, U.S. National Library of Medicine. Vitamin A (encyclopedia article, reviewed 1/21/2025). Read 2026-10-22.
  11. MedlinePlus, U.S. National Library of Medicine. Vitamin K (encyclopedia article, reviewed 1/21/2025). Read 2026-10-22.
  12. NHS (UK). Vitamins and minerals: Vitamin A. Page last reviewed 3 August 2020. Read 2026-10-22.
  13. MedlinePlus, U.S. National Library of Medicine. Vitamin E (encyclopedia article, reviewed 1/21/2025). Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.