Minerals, Supplements and Kidney Disease
Why potassium, phosphorus and magnesium need extra care in chronic kidney disease, what NIDDK, the NHS and the National Kidney Foundation say, and why to ask the kidney team before any supplement.
Content last updated . This page has not been medically reviewed.
Overview
Healthy kidneys balance salts and minerals in the blood. When kidney function falls, minerals such as potassium and phosphorus can build up. [2] This page explains the main minerals of concern and what the sources say. It does not tell anyone what to take. Limits for a person with CKD are set by their clinician using blood tests, the stage of disease and treatment. Evidence labels: established guidance (patient guidance from NIDDK, NHS or the National Kidney Foundation), review (a published review), and Proper evidence not found.The minerals that matter most
| Mineral | What the sources say | Source |
|---|---|---|
| Potassium | CKD can make it harder for the kidneys to remove potassium, so levels in the blood can become very high. Too little or too much can cause heart and muscle problems, so the right amount is worked out with a dietitian or health care professional. | [2] |
| Phosphorus | Damaged kidneys cannot remove it as well as healthy kidneys can; too much in the blood can harm blood vessels and make bones thin and weak. Added phosphorus in processed foods is the main source for many people. | [2] |
| Magnesium | In more advanced CKD (creatinine clearance below 30 mL/min) the kidney's compensation becomes inadequate, and high magnesium develops frequently below 10 mL/min. In dialysis patients, nutrition and medicines such as laxatives or antacids also play an important role. | [3] |
| Sodium and salt | The NHS says a dietitian may advise on potassium, phosphate and salt if blood tests show high potassium and phosphate. | [1] |
Supplements and everyday products to check
- Potassium supplements and salt substitutes. NIDDK says salt substitutes can be high in potassium and to limit foods with potassium chloride on the ingredient list. [2] The NHS (UK) says older people should not take potassium supplements unless advised by a doctor, because their kidneys may be less able to remove potassium. [4] MedlinePlus lists poor kidney function, ACE inhibitors, ARBs and potassium-sparing diuretics among common causes of high blood potassium. [5]
- Phosphorus additives. NIDDK says to look for "phosphorus" or words with "PHOS" on ingredient lists, such as phosphoric acid and disodium phosphate. [2] The National Kidney Foundation says phosphorus from food additives is completely absorbed. [6]
- Magnesium products and antacids. The review says laxatives or antacids affect magnesium balance in dialysis patients. [3] MedlinePlus says magnesium excess most often occurs with magnesium supplements or magnesium-containing laxatives. [7]
- Phosphate binders. These are medicines, not supplements: NIDDK describes them as medicines that bind phosphorus from food in the stomach so it is not absorbed. [2] Use them only as prescribed.
- Herbal products. The National Kidney Foundation says "natural" does not always mean "safe" for people with CKD, and herbal supplements can worsen kidney disease or interact with prescribed medicines. [8]
- Calcium. MedlinePlus says higher calcium intake over a long period raises the risk of kidney stones in some people. [9] See Calcium supplements, heart disease and kidney stones.
Is a special diet needed?
The NHS says if you have CKD you may not need a special diet, and that a healthy, balanced diet can help. If blood tests show high potassium and phosphate, you may be referred to a dietitian. [1] Individual advice depends on stage, treatment and blood results.Other situations to mention
Tell the kidney team about pregnancy or breastfeeding, a child with kidney disease, liver disease, planned surgery or dialysis, because each can change which supplements are suitable. See Supplements before surgery and Medication interactions.Related pages
Existing conditions, Older adults and Mineral toxicity and upper limits.Frequently asked questions
Can I take magnesium if I have kidney disease?
Ask your kidney team first. A review says magnesium builds up in advanced CKD, and laxatives and antacids can contribute. [3]
Are salt substitutes safe in CKD?
NIDDK says salt substitutes can be high in potassium. Ask your kidney team or dietitian before using one. [2]
Do I need a low-potassium diet?
Only if advised for you. The NHS says a dietitian gives dietary advice when blood tests show high potassium and phosphate. [1]
Are herbal supplements safer because they are natural?
The National Kidney Foundation says natural does not always mean safe in CKD. [8]
Where can I check which products to avoid?
Your pharmacist can check your whole list of medicines and supplements against your kidney function. [1]
More details: evidence, limits and cautions
The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.
Safety first
What we could not find
References
- NHS. Chronic kidney disease: living with (page last reviewed 22 March 2023). NHS. Chronic kidney disease: living with (page last reviewed 22 March 2023). Read 2026-10-23.
- NIDDK (US National Institutes of Health). Eating and nutrition for chronic kidney disease. NIDDK (US National Institutes of Health). Eating and nutrition for chronic kidney disease. Read 2026-10-23.
- Cunningham J, Rodriguez M, Messa P. Magnesium in chronic kidney disease Stages 3 and 4 and in dialysis patients. Clin Kidney J. 2012. Cunningham J, Rodriguez M, Messa P. Magnesium in chronic kidney disease Stages 3 and 4 and in dialysis patients. Clin Kidney J. 2012. Read 2026-10-23.
- NHS. Vitamins and minerals: Others (chromium, copper, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, salt, zinc; page last reviewed 3 August 2020). NHS. Vitamins and minerals: Others (chromium, copper, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, salt, zinc; page last reviewed 3 August 2020). Read 2026-10-23.
- MedlinePlus (US National Library of Medicine). Potassium in diet. MedlinePlus (US National Library of Medicine). Potassium in diet. Read 2026-10-23.
- National Kidney Foundation (US). Phosphorus and your CKD diet (last updated 16 July 2024). National Kidney Foundation (US). Phosphorus and your CKD diet (last updated 16 July 2024). Read 2026-10-23.
- MedlinePlus (US National Library of Medicine). Magnesium in diet. MedlinePlus (US National Library of Medicine). Magnesium in diet. Read 2026-10-23.
- National Kidney Foundation (US). Herbal supplements and kidney disease (last updated 5 September 2025). National Kidney Foundation (US). Herbal supplements and kidney disease (last updated 5 September 2025). Read 2026-10-23.
- MedlinePlus (US National Library of Medicine). Calcium in diet. MedlinePlus (US National Library of Medicine). Calcium in diet. Read 2026-10-23.