Chaga Side Effects, Oxalates and Kidney Concerns
Case reports link chaga powder to oxalate kidney injury, some needing dialysis. What the reports say, what is not known, and the bleeding and blood sugar medicine cautions.
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Safety first. Supplements can cause side effects and interact with medicines. Read mushroom safety and interactions before you use any mushroom product.
Kidney warning first. Doctors in Japan and Korea have published case reports of serious kidney injury in people who took chaga (Inonotus obliquus) powder, with oxalate crystals found in kidney tissue. In two of three cases summarized by Memorial Sloan Kettering Cancer Center (MSK), dialysis was needed and kidney function did not recover. [1] If you have kidney disease, reduced kidney function or a kidney transplant, ask your kidney specialist or pharmacist before using chaga in any form. This page describes reports and is not advice for any one person.
What chaga is
Chaga is Inonotus obliquus (Fr.) Pilát, family Hymenochaetaceae, an accepted fungal species. [2] MSK says it is commonly found on birch trees in cold climates and is used in folk medicine across northern Europe, and that the conk used medicinally includes wood from the host tree together with the fungus. [1] For the full profile see chaga.What the case reports describe
| Case | What was taken | What happened |
|---|---|---|
| 72-year-old woman, Japan, 2014 | Chaga powder, 4 to 5 teaspoons a day for 6 months, taken for liver cancer | Kidney function fell and dialysis was started. Biopsy showed oxalate crystals, and oxalate nephropathy was diagnosed. [3] MSK adds that kidney function did not recover. [1] |
| 49-year-old man, Korea, 2020 | Chaga powder, long-term, for atopic dermatitis | He arrived with end-stage kidney disease. Biopsy showed oxalate deposits, and the leftover powder measured 14.2 per 100 g oxalate. [4] |
| 69-year-old man, Korea, 2022 | Chaga powder, 10 to 15 g a day, plus vitamin C 500 mg a day for 3 months | Acute kidney injury with oxalate crystals; function recovered about a month after dialysis and high-dose steroids. [5] |
The amounts are what each report recorded. They are not safe or unsafe thresholds, and they are not recommendations. The authors of the 2014 report called these mushrooms extremely high in oxalate, and the 2020 authors called chaga a potential risk factor for chronic kidney disease given its oxalate content. [3][4]
Animal evidence
A 2026 study in rats gave chaga powder at amounts scaled from a clinical case. The highest-dose group had oxalate crystal deposits, tubular injury and more protein in the urine; the authors concluded that high-dose consumption may damage the kidneys. [6] This is animal research at high amounts and does not tell us the risk to a person who uses a small amount.What is not known
- How common this is. We found case reports only, with no study counting how often it happens. Case reports can show a problem exists but cannot show how likely it is.
- Whether tea, extracts and capsules carry the same risk. The reports describe powder. Oxalate content of tea or extracts is not described in the sources we read. MSK's patient text says it is generally safe to drink as a tea, while its clinician section lists the kidney cases, so ask a clinician rather than assume. [1] See chaga tea, powder and extracts.
- Who is most at risk. The sources we read do not define it, so asking a kidney specialist first is the cautious course.
Medicine cautions
MSK says to talk with your healthcare provider if you take blood thinners such as warfarin, because chaga may increase bleeding risk. [1] Its clinician section notes that chaga extract inhibited platelet clumping in mice and that the clinical relevance is not known, and that chaga had additive blood-sugar-lowering effects in laboratory tests with unknown clinical significance. [1] Ask a pharmacist before combining chaga with blood thinners, antiplatelet medicines or diabetes medicines, and tell the surgical team before any procedure. See how interactions work and supplements before surgery.Other groups
Pregnancy, breastfeeding, children, older adults and liver safety are not described for chaga in the sources we read. Contamination and mislabeling of chaga products are not described either; see quality testing and certifications. MSK also says natural reserves of the fungus have nearly been exhausted and that scientists are seeking cultivated substitutes, which is one reason the species label and source matter. [1]When to get help
If you feel unwell or notice any change in your health while using chaga, stop it and contact a clinician promptly. Call 911 for collapse or severe symptoms. To report a reaction see side effects and reporting. For wider kidney questions see mushrooms, the kidneys, oxalates and the liver and minerals and kidney disease.Frequently asked questions
Can chaga damage the kidneys?
Case reports link chaga powder to oxalate kidney injury, and one required long-term dialysis. A rat study found kidney injury at high amounts. [1][6]
Why is oxalate the concern?
Chaga was measured as high in oxalate, and kidney biopsies in the reports showed oxalate crystals. [4][3]
Is chaga tea safer than powder?
Not established in the sources we read. The reports describe powder, so ask a clinician if you have kidney disease. [5]
Can chaga interact with warfarin?
MSK says chaga may increase bleeding risk and advises talking with your healthcare provider if you take warfarin or similar blood thinners. [1]
Does chaga have other side effects?
MSK's patient text says no side effects have been reported, yet its clinician section lists kidney injury cases. Absence of reports is not proof of safety. [1]
References
- Memorial Sloan Kettering Cancer Center, Chaga Mushroom, About Herbs, Botanicals & Other Products (last updated 2023-02-20). Read 2026-10-23.
- Global Biodiversity Information Facility (GBIF), species match for Inonotus obliquus, usage key 2521089, family Hymenochaetaceae. GBIF species page. Read 2026-10-23 through the GBIF species-match service.
- Kikuchi Y et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014. Read 2026-10-23.
- Lee S et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci 2020. Read 2026-10-23.
- Kwon O et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: a case report. Medicine (Baltimore) 2022. Read 2026-10-23.
- Lee S et al. Kidney injury induced by high-dose chaga mushroom consumption: experimental evidence in a rat model. J Korean Med Sci 2026. Read 2026-10-23.