Holistic Remedies · Ingredient
Mtl
Formula: C6H14O6 · MW: 182.172 · Drug-likeness: 0.261
⚗️ Identity
Name
Mtl
Aliases / Synonyms
D-mannitol; mannitol; 69-65-8; Mannite; Osmitrol; Manna sugar; Cordycepic acid; Osmofundin; Resectisol; Diosmol
🧪 Chemistry
Molecular Weight
182.1720
LogP
-3.5854
Drug-likeness
0.261
Oral Bioavailability
17.7350
H-Bond Acceptors
6
H-Bond Donors
6
Rotatable Bonds
5
🔗 External References
59
Clinical Trials
14
Meta-Analyses
0
PubMed References
Top Conditions Studied with Mtl
Cystic Fibrosis 8
Asthma 7
Bronchiectasis 3
Pain 2
Amount of Pulpal anaesthesia 1
Brain Tumor|Tumor, Brain|Brain Neoplasm|Neoplasm, Supratento 1
Irreversible Pulpitis 1
Anaplastic Oligoastrocytoma|Anaplastic Oligodendroglioma|Mix 1
Perioperative care 1
Cough|Bronchial Hyperreactivity 1
Supratentorial Tumors 1
Brain Tumor|Intracranial Pressure 1
📋 Sample Trials
NCT02728687
Topical Menthol +/- Mannitol for Painful Diabetic Peripheral Neuropathy
Completed · Phase 1|Phase 2 · Diabetic Peripheral Neuropathy
NCT02760862
Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache
Completed · Phase 4 · Headache
NCT00117208
Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis
Completed · Phase 2 · Cystic Fibrosis
NCT00199511
Hypertonic Saline 75% vs Mannitol 20%
Completed · Brain Tumor|Tumor, Brain|Brain Neoplasm|
NCT00251056
Mannitol Dose Response Study in Cystic Fibrosis
Completed · Phase 2 · Cystic Fibrosis
NCT00293475
Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Unknown · Phase 1|Phase 2 · Central Nervous System Lymphoma
📊 Sample Meta-Analyses
CRD42020156824
The use of mannitol to prevent cisplatin-induced nephrotoxicity: A systematic review
Cisplatin is a chemotherapeutic agent widely used for various types of tumor. Ho
CRD42021253990
Protective effect of mannitol on cisplatin-induced nephrotoxicity：a systematic review and meta-analysis
Cisplatin is a basic and widely used chemotherapeutic agent used in the treatmen
CRD42022324278
The use of mannitol for acute intracranial hypertension in a pediatric population.
The treatment of acute intracranial hypertension in a pediatric population with
CRD42022316298
To evaluate hypertonic saline solution treatment versus mannitol for elevated intracranial pressure in adult patients with traumatic brain injury: A comparative systematic review
Increased intracranial pressure in secondary brain injury is one of the leading
CRD42020151300
Perioperative use of intravenous mannitol in partial nephrectomy
Mannitol is often used perioperatively in partial nephrectomy and other kidney s
CRD42020218252
Comparison of the effects of 3% hypertonic saline and 20% mannitol in patients undergoing brain tumor Surgery
One of the important goals of anaesthetic management for patients undergoing cra
📚 Sample References
None linked yet.
🏥 Linked Health Topics 12 · matched via study conditions