Holistic Remedies · Ingredient
Tetramethylpyrazine
Formula: C8H12N2 · MW: 136.198 · Drug-likeness: 0.542
⚗️ Identity
Name
Tetramethylpyrazine
Aliases / Synonyms
2,3,5,6-Tetramethylpyrazine; 1124-11-4; Ligustrazine; Pyrazine, tetramethyl-; Bs factor; Tetrapyrazine; Tetramethylpyrazin; Chuanxiongzine; Liqustrazine
🧪 Chemistry
Molecular Weight
136.1980
LogP
1.7103
Drug-likeness
0.542
Oral Bioavailability
20.0070
H-Bond Acceptors
2
🔗 External References
HERB DB
PubChem CID
CAS Number
DrugBank
InChIKey
FINHMKGKINIASC-UHFFFAOYSA-N
0
Clinical Trials
9
Meta-Analyses
0
PubMed References
Top Conditions Studied with Tetramethylpyrazine
Gestational hypertension is a disease that affects 5% to 10% 1
Diabetic nephropathy is typically defined by albuminuria and 1
Stroke is a common disorder. It is due either to blockage of 1
Stable angina refers to the classic type of angina related t 1
Since the introduction of the term vertebrobasilar insuffici 1
Ischemic stroke is the leading cause of death and disability 1
Idiopathic pulmonary fibrosis(IPF) is a different type of ch 1
📋 Sample Trials
None linked yet.
📊 Sample Meta-Analyses
CRD42012003285
Ligustrazine for diabetic kidney disease
Diabetic nephropathy is typically defined by albuminuria and abnormal renal func
CRD42018105921
The clinical efficacy of tanshinol combined with ligustrazine in the treatment of stable angina: a systematic review and meta-analysis
Stable angina refers to the classic type of angina related to myocardial ischemi
CRD42020163628
Effects and potential mechanism(s) of ligustrazine for the treatment of diabetic nephropathy: A Preclinical Systematic Review and Meta-analysis
CRD42020164851
Clinical efficacy and safety of Salvia ligustrazine injection for the treatment of vertebral-basilar insufficiency for a meta-analysis and systematic review
Since the introduction of the term vertebrobasilar insufficiency in 1946, it has
CRD42020170240
The efficacy and safety of ligustrazine in stroke.
Stroke is a common disorder. It is due either to blockage of an artery in the br
CRD42020193626
Meta-analysis of clinical efficacy and safety of ligustrazine in the treatment of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis(IPF) is a different type of chronic progressive pu
📚 Sample References
None linked yet.