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Each record is a registered study, a systematic-review registration or a publication. A registered or ongoing study is not a finding, and animal or cell research does not show an effect in people. The same study can appear under more than one subject, so the number of records is not a count of independent studies. You can also search an exact DOI, PubMed ID, NCT or CRD number. How to read these records.

19 study records (showing up to 30 per record type)

• Systematic review registration CRD42023413131 Registered protocol, no results here: Review Ongoing
  Effect of dietary alpha-linolenic acid supplementation on inflammatory biomarkers in individuals with dyslipidemias: A systematic review and meta-analysis of randomized controlled trials
  Condition or outcome area: Dyslipidemias.
  2023-04-10 · Subject: Zi Su Ye You; 紫苏叶油; Perilla Oil; Oleum Folii Perillae · open the herb record
• Systematic review registration CRD42021255527 Registered protocol, no results here: Review Completed published
  Perillyl alcohol for cancer treatment
  Condition or outcome area: Cancer treatment
  2021-06-18 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: Perillic acid; 7694-45-3; (-)-perillic acid; Perillicacid; 4-Isopropenylcyclohex-1-enecarboxylic acid; 4-prop-1-en-2-ylcyclohexene-1-carboxylic acid; PKS69DU4ZQ; 4-(1-methylethenyl)-1-cyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-; CHEBI:36999 · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: Perillaldehyde; Perillyl aldehyde; 2111-75-3; Perilla aldehyde; Perillal; Perillic aldehyde; P-Mentha-1,8-dien-7-al; Dihydrocuminyl aldehyde; 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde · open the ingredient record
• Systematic review registration CRD42018082207 Registered protocol, no results here: Review Ongoing
  Limonene, perillyl alcohol, perillic acid and perillaldehyde as anticancer agents: a systematic review
  Condition or outcome area: Cancer treatment Cancer prevention
  2018-01-04 · Subject: L-limonen; Limonene, (-)-; (-)-Limonene; 5989-54-8; l-Limonene; (S)-(-)-Limonene; (S)-Limonene; (S)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-1-ene; beta-Limonene; (-)-(4S)-Limonene · open the ingredient record
• Publication PMID 36070663 Research model: Animal Experiment
  Perillyl alcohol attenuates chronic restraint stress aggravated dextran sulfate sodium-induced ulcerative colitis by modulating TLR4/NF-κB and JAK2/STAT3 signaling pathways
  Condition or outcome area: chronic inflammatory immune bowel disease; ulcerative colitis; Ulcerative colitis; chronic inflammation; decreased ulcerations
  Phytomedicine · 2022 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record · DOI 10.1016/j.phymed.2022.154415
• Publication PMID 35030388 Research model: Animal & Cell Experiment
  Perillyl alcohol attenuates rheumatoid arthritis via regulating TLR4/NF-κB and Keap1/Nrf2 signaling pathways: A comprehensive study onin-vitro and in-vivo experimental models
  Condition or outcome area: joint inflammation; arthritis; Rheumatoid arthritis; bone erosion; rheumatoid arthritis; chronic and idiopathic autoimmune disorder; pannus
  Phytomedicine · 2022 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record · DOI 10.1016/j.phymed.2022.153926
• Publication PMID 34929480 Research model: Animal & Cell Experiment
  Perillyl alcohol inhibits keratinocyte proliferation and attenuates imiquimod-induced psoriasis like skin-inflammation by modulating NF-κB and STAT3 signaling pathways
  Condition or outcome area: psoriatic like skin inflammation; chronic inflammatory and proliferative skin disease; epidermal hyperplasia; splenomegaly; imiquimod; skin lesions; psoriasis; acanthosis; psoriasis-like skin inflammation; Psoriasis; hyper-keratosis
  Int Immunopharmacol · 2021 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record · DOI 10.1016/j.intimp.2021.108436
• Publication PMID 33649109 Research model: Animal Experiment
  Perillyl alcohol reduces parasite sequestration and cerebrovascular dysfunction during experimental cerebral malaria
  Condition or outcome area: vascular dysfunction; Cerebral malaria; cerebrovascular dysfunction; inflammatory infiltrates; immunovasculopathy; cerebral oedema; Cerebral Malaria
  Antimicrob Agents Chemother · 2021 · Subject: Perillyl alcohol; 536-59-4; Perilla alcohol; Perillol; Isocarveol; p-Mentha-1,8-dien-7-ol; Hydrocumin alcohol; 1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-; Dihydrocuminyl alcohol; Iso-carveol · open the ingredient record · DOI 10.1128/AAC.00004-21
• Publication PMID 35204061 Research model: Animal & Cell Experiment
  Therapeutic Potential of Perillaldehyde in Ameliorating Vulvovaginal Candidiasis by Reducing Vaginal Oxidative Stress and Apoptosis
  Condition or outcome area: Vulvovaginal candidiasis; Candida albicans
  Antioxidants (Basel) · 2022 · Subject: Perillaldehyde; Perillyl aldehyde; 2111-75-3; Perilla aldehyde; Perillal; Perillic aldehyde; P-Mentha-1,8-dien-7-al; Dihydrocuminyl aldehyde; 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde · open the ingredient record · DOI 10.3390/antiox11020178
• Publication PMID 34903262 Research model: Animal & Cell Experiment
  Perillaldehyde improves cognitive function in vivo and in vitro by inhibiting neuronal damage via blocking TRPM2/NMDAR pathway
  Condition or outcome area: vascular dementia; cognitive dysfunction syndrome; cerebrovascular diseases; epilepsy; insomnia; Vascular cognitive dysfunction; central nervous system diseases
  Chin Med · 2021 · Subject: Perillaldehyde; Perillyl aldehyde; 2111-75-3; Perilla aldehyde; Perillal; Perillic aldehyde; P-Mentha-1,8-dien-7-al; Dihydrocuminyl aldehyde; 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde · open the ingredient record · DOI 10.1186/s13020-021-00545-9
• Publication PMID 34738877 Research model: Cell Experiment
  Perillaldehyde inhibits bone metastasis and receptor activator of nuclear factor-κB ligand (RANKL) signaling-induced osteoclastogenesis in prostate cancer cell lines
  Condition or outcome area: prostate cancer; PCa; cancer
  Bioengineered · 2021 · Subject: Perillaldehyde; Perillyl aldehyde; 2111-75-3; Perilla aldehyde; Perillal; Perillic aldehyde; P-Mentha-1,8-dien-7-al; Dihydrocuminyl aldehyde; 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde · open the ingredient record · DOI 10.1080/21655979.2021.2001237
• Publication PMID 32822688 Research model: Animal & Cell Experiment
  Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis
  Condition or outcome area: oropharyngeal candidiasis
  Biochem Pharmacol · 2020 · Subject: Perillaldehyde; Perillyl aldehyde; 2111-75-3; Perilla aldehyde; Perillal; Perillic aldehyde; P-Mentha-1,8-dien-7-al; Dihydrocuminyl aldehyde; 1-Cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)-; 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde · open the ingredient record · DOI 10.1016/j.bcp.2020.114201
• Publication PMID 35058774 Research model: Animal Experiment
  Perilla Leaf Extract (PLE) Attenuates COPD Airway Inflammation via the TLR4/Syk/PKC/NF-κB Pathway In Vivo and In Vitro
  Condition or outcome area: COPD inflammation; Chronic obstructive pulmonary disease; airway inflammation; tumor; respiratory disease; COPD airway inflammation
  Front Pharmacol · 2022 · Subject: Zi Su Ye; 紫苏叶; Perilla Leaf; Folium Perillae; Perillae Folium · open the herb record · DOI 10.3389/fphar.2021.763624
• Publication PMID 36420586 Research model: Cell Experiment
  Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation
  Condition or outcome area: kidney injury; chronic kidney disease; renal injury
  Phytother Res · 2022 · Subject: Zi Su; 紫苏; Perilla Frutescens · open the herb record · DOI 10.1002/ptr.7684
• Publication PMID 34899287 Research model: Cell Experiment
  Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology
  Condition or outcome area: Chronic kidney disease; chronic progressive disease; chronic renal failure; multi-system damage
  Front Pharmacol · 2021 · Subject: Zi Su; 紫苏; Perilla Frutescens · open the herb record · DOI 10.3389/fphar.2021.717744
• Publication PMID 33921322 Research model: Cell Experiment
  Perilla frutescens Extracts Enhance DNA Repair Response in UVB Damaged HaCaT Cells
  Nutrients · 2021 · Subject: Zi Su; 紫苏; Perilla Frutescens · open the herb record · DOI 10.3390/nu13041263
• Publication PMID 31743741 Research model: Animal Experiment
  Perilla oil regulates intestinal microbiota and alleviates insulin resistance through the PI3K/AKT signaling pathway in type-2 diabetic KKAy mice
  Condition or outcome area: diabetic; type-2 diabetic KKAy; type 2 diabetes mellitus
  Food Chem Toxicol · 2020 · Subject: Zi Su; 紫苏; Perilla Frutescens · open the herb record · DOI 10.1016/j.fct.2019.110965