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Acupuncture for Chemotherapy-Induced Nausea and Vomiting: Evidence

What reviews and trials show about acupuncture and acupressure for nausea and vomiting caused by chemotherapy, including why the certainty of evidence is low.

Content last updated . This page has not been medically reviewed.

Why this page matters

Nausea and vomiting can be hard side effects of chemotherapy. Acupuncture is sometimes offered alongside anti-sickness medicine. This page reports what research found for chemotherapy-induced nausea and vomiting (often shortened to CINV). It is information only and does not replace your cancer team's advice.

Where the evidence stands

Most agreement about acupuncture for cancer treatment nausea rests on research done before current anti-sickness guidelines, so it is uncertain whether acupuncture helps when added to today's standard treatment. [1] The National Cancer Institute's PDQ summary calls the chemotherapy nausea studies the most convincing in cancer acupuncture research, because those studies benefit from scientifically sound designs. [2]
Review or trialWhat it foundReading it
2023 review, 38 trials, 2,503 peopleAcupuncture added to usual care may increase complete control of acute vomiting (risk ratio 1.13) and delayed vomiting (1.47); no effect on other outcomes [3]Certainty generally low or very low
2026 umbrella review, 8 prior reviewsInvasive acupuncture may help delayed CINV; included reviews were generally low quality [4]Needs better trials
2026 review, 49 trials, 4,133 peopleLess vomiting and nausea than comparison groups; comparison was sham or conventional treatment [5]Pooling very different comparators
2020 trial, 134 people with advanced cancerReal and sham acupuncture did not differ; CINV scores were low throughout, leaving little room to improve [2]No difference from sham

Label: promising but limited. Two things hold the evidence back. First, many trials compare acupuncture with usual care only, which cannot separate the needles from attention, expectation and hope. A sham-controlled design can address part of this but not all of it, and patients cannot always be blinded. Second, a 2025 study of English-language trials found selective outcome-reporting bias: only four of eleven had a trial registry, and none reported all outcomes as planned. [6]

Pressure and wristbands

Wristbands and finger pressure on the wrist point PC6 are needle-free options. In a three-group trial of 500 people having chemotherapy, nausea in the first cycle did not differ significantly between real wristbands, sham wristbands and antiemetics alone. [7] The NCI summary describes a small 2016 trial of ear-seed acupressure that reported less nausea, but it had 48 people and no placebo control. [2] See acupressure wristbands and nausea and ear seeds.

Evidence is also mixed by point. A placebo-controlled trial in 103 liver cancer patients found stimulation of the K1 point plus antiemetics did not prevent nausea. [2]

What a session may involve

An acupuncturist places fine needles at points on the body; some practices add small electrical current. See electroacupuncture and what to expect at a first appointment. Frequency, timing around chemotherapy days and needle sites should be agreed with your oncology team.

Care first

Do not use acupuncture to postpone seeing a health care provider. [1] Call your cancer team promptly if you cannot keep fluids down or medicines are not controlling vomiting. Call 911 for an emergency.

Frequently asked questions

Does acupuncture help with chemotherapy nausea?

It might help with vomiting when added to usual care, but certainty is low or very low. [3]

Can acupuncture replace anti-sickness medicine?

No source read here supports that. The trials tested acupuncture added to usual care or compared with sham, and NCCIH says it is uncertain whether acupuncture helps on top of current standard treatment. [1]

Do acupressure wristbands help with chemotherapy nausea?

In a 500-person trial, real and sham wristbands did not differ significantly. [7]

Is acupuncture safe during cancer treatment?

Serious problems are uncommon but possible, and bleeding risk matters. [1] [8] Ask your oncology team first.

Why do reviews disagree?

They pool trials with different comparators, such as sham or usual care, and many trials were small or at risk of bias. [4] [6]

More details: evidence, limits and cautions

The details behind this page: cautions, limits of the evidence and where sources disagree. Open any note to read it.

Safety
Acupuncture complications are rare, but improper delivery can cause serious adverse effects, including infection, punctured organs and nerve injury. [1] The NHS lists blood-thinning medicine and a higher risk of bleeding as reasons acupuncture may not be safe. [8] Tell your cancer team before starting and ask whether anything in your treatment makes needling unwise. See acupuncture in cancer care and side effects and precautions.
References
  1. NCCIH, Acupuncture: Effectiveness and Safety. Read 2026-10-22.
  2. National Cancer Institute, Acupuncture (PDQ) Health Professional Version. Read 2026-10-22.
  3. Acupuncture for the prevention of chemotherapy-induced nausea and vomiting in cancer patients: a systematic review and meta-analysis. Cancer Med. 2023. PubMed 37226372 Read 2026-10-22.
  4. Acupuncture for chemotherapy-induced nausea and vomiting: an umbrella review of systematic reviews. Complement Ther Med. 2026. PubMed 42772702 Read 2026-10-22.
  5. Efficacy and safety of acupuncture for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis of randomized controlled trial. Front Neurol. 2026. PubMed 42490841 Read 2026-10-22.
  6. High outcome-reporting bias in randomized-controlled trials of acupuncture for cancer chemotherapy-induced nausea and vomiting. Curr Oncol. 2025. PubMed 40862831 Read 2026-10-22.
  7. Molassiotis A, et al. The effectiveness of acupressure for the control and management of chemotherapy-related acute and delayed nausea: a randomized controlled trial. J Pain Symptom Manage. 2014. PubMed 23602325 Read 2026-10-22.
  8. NHS, Herbal medicines and complementary therapies. Read 2026-10-22.
Education, not medical advice. This page is for general information. It does not diagnose or treat any condition and is not a substitute for care from a qualified health professional. Natural does not automatically mean safe. Ask a clinician or pharmacist before changing your care, especially if you take medication, are pregnant or breastfeeding, or have a health condition.